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Chemotherapy-induced neutropenia does not correlate with DNA repair gene polymorphisms and treatment efficacy in advanced non-small-cell lung cancer patients.

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Chemotherapy-induced neutropenia does not correlate with DNA repair gene polymorphisms and treatment efficacy in advanced non-small-cell lung cancer patients.

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Sirera Pérez, R. (2011). Chemotherapy-induced neutropenia does not correlate with DNA repair gene polymorphisms and treatment efficacy in advanced non-small-cell lung cancer patients. Clinical Lung Cancer. 12(4):224-230. doi:10.1016/j.cllc.2011.03.023

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/65057

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Título: Chemotherapy-induced neutropenia does not correlate with DNA repair gene polymorphisms and treatment efficacy in advanced non-small-cell lung cancer patients.
Autor:
Entidad UPV: Universitat Politècnica de València. Departamento de Biotecnología - Departament de Biotecnologia
Fecha difusión:
Resumen:
[EN] Background: Platinum doublets are standard chemotherapy for advanced non-small-cell lung cancer (NSCLC). The aim of this study was to assess whether neutropenia is: (1) an indicator for treatment efficacy, or (2) ...[+]
Palabras clave: Advanced disease , Chemotherapy , Efficacy to therapy , NSCLC , SNP , Cisplatin , Docetaxel , Excision repair cross complementing protein 1 , Unclassified drug , Xeroderma pigmentosum group D protein , Xeroderma pigmentosum group D protein 10 , Xeroderma pigmentosum group D protein 23 , XRCC3 protein , Advanced cancer , Article , Cancer combination chemotherapy , Chemotherapy induced neutropenia , DNA repair , Drug dose reduction , Drug dose regimen , Drug efficacy , Drug induced disease , Gene frequency , Human , Lung non small cell cancer , Multiple cycle treatment , Neutropenia , Overall survival , Prognosis , Sex difference , Single nucleotide polymorphism , Treatment response , Adenocarcinoma , Adult , Aged , Antineoplastic Combined Chemotherapy Protocols , Carcinoma, Large Cell , Carcinoma, Non-Small-Cell Lung , Carcinoma, Squamous Cell , DNA-Binding Proteins , Endonucleases , Female , Follow-Up Studies , Humans , Lung Neoplasms , Male , Middle Aged , Neoplasm Staging , Polymorphism, Genetic , Retrospective Studies , Survival Rate , Taxoids , Treatment Outcome
Derechos de uso: Cerrado
Fuente:
Clinical Lung Cancer. (issn: 1525-7304 )
DOI: 10.1016/j.cllc.2011.03.023
Editorial:
Elsevier
Versión del editor: https://dx.doi.org/10.1016/j.cllc.2011.03.023
Tipo: Artículo

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