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The causes of epistasis in genetic networks

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The causes of epistasis in genetic networks

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Macia, J.; Sole, RV.; Elena Fito, SF. (2012). The causes of epistasis in genetic networks. Evolution. 66(2):586-596. doi:10.1111/j.1558-5646.2011.01451.x

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Title: The causes of epistasis in genetic networks
Author: Macia, Javier Sole, Ricard V. Elena Fito, Santiago Fco
UPV Unit: Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes
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[EN] Epistasis refers to the nonadditive interactions between genes in determining phenotypes. Considerable efforts have shown that, even for a given organism, epistasis may vary both in intensity and sign. Recent comparative ...[+]
Subjects: Complexity , Degeneracy , Feedback loops , Redundancy , Robustness
Copyrigths: Reserva de todos los derechos
Evolution. (issn: 0014-3820 )
DOI: 10.1111/j.1558-5646.2011.01451.x
Publisher version: http://dx.doi.org/10.1111/j.1558-5646.2011.01451.x
Project ID:
Santa Fe Institute
We thank J. Carrera, J. A. G. M. de Visser, M. A. Fares, and S. Valverde for discussions and two anonymous reviewers for insightful suggestions. This work was supported by the Spanish Ministry of Science and Innovation ...[+]
Type: Artículo

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