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MicroRNA precursors are not structurally robust but plastic

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MicroRNA precursors are not structurally robust but plastic

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Rodrigo Tarrega, G.; Elena Fito, SF. (2013). MicroRNA precursors are not structurally robust but plastic. Genome Biology and Evolution. 5(1):181-186. https://doi.org/10.1093/gbe/evs132

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Title: MicroRNA precursors are not structurally robust but plastic
Author: Rodrigo Tarrega, Guillermo Elena Fito, Santiago Fco
UPV Unit: Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes
Issued date:
Abstract:
Robustness is considered a ubiquitous property of living systems at all levels of organization, and small noncoding RNA (sncRNA) is a genuine model for its study at the molecular level. In this communication, we question ...[+]
Subjects: Conformational flexibility , Evolvability , Noncoding RNA , Secondary structure , Thermodynamics
Copyrigths: Reserva de todos los derechos
Source:
Genome Biology and Evolution. (issn: 1759-6653 )
DOI: 10.1093/gbe/evs132
Publisher:
Oxford University Press (OUP)
Publisher version: http://dx.doi.org/10.1093/gbe/evs132
Project ID:
EMBO long-term fellowship
Marie Curie actions ALTF-1177-2011
info:eu-repo/grantAgreement/MINECO//BFU2012-30805/ES/EVOLUTIONARY SYSTEMS VIROLOGY: EPISTASIS AND THE RUGGEDNESS OF ADAPTIVE LANDSCAPES, MUTATIONS IN REGULATORY SEQUENCES, AND THE HOST DETERMINANTS OF VIRAL FITNESS/
Thanks:
The authors thank R. B. R. Azevedo for useful comments. This work was supported by an EMBO long-term fellowship co-funded by Marie Curie actions (ALTF-1177-2011) to G. R. and by grant BFU2012-30805 from the Spanish Secretaria ...[+]
Type: Artículo

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