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Seeking the mechanism responsible for fluoroquinolone photomutagenicity: a pulse radiolysis, steady-state, and laser flash photolysis study

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Seeking the mechanism responsible for fluoroquinolone photomutagenicity: a pulse radiolysis, steady-state, and laser flash photolysis study

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Soldevila Serrano, S.; Cuquerella Alabort, MC.; Lhiaubet-Vallet, V.; Edge, R.; Bosca Mayans, F. (2014). Seeking the mechanism responsible for fluoroquinolone photomutagenicity: a pulse radiolysis, steady-state, and laser flash photolysis study. Free Radical Biology and Medicine. 67:417-425. doi:10.1016/j.freeradbiomed.2013.11.027

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/70217

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Title: Seeking the mechanism responsible for fluoroquinolone photomutagenicity: a pulse radiolysis, steady-state, and laser flash photolysis study
Author:
UPV Unit: Universitat Politècnica de València. Instituto Universitario Mixto de Tecnología Química - Institut Universitari Mixt de Tecnologia Química
Issued date:
Abstract:
The mechanism responsible for the remarkable photomutagenicity of fluoroquinolone (FQ) antibiotics remains unknown. For this reason, it was considered worthwhile to study in detail the interactions between DNA and a ...[+]
Subjects: Carcinogenicity , DNA , Fluoroquinolones , Genotoxicity , Photolysis , Photochemistry , Free radicals
Copyrigths: Cerrado
Source:
Free Radical Biology and Medicine. (issn: 0891-5849 )
DOI: 10.1016/j.freeradbiomed.2013.11.027
Publisher:
Elsevier
Publisher version: http://dx.doi.org/10.1016/j.freeradbiomed.2013.11.027
Thanks:
We thank Professor Suppiah Navaratnam for his help. We acknowledge the Spanish government for Grants CTQ2010-19909 and CTQ2012-32621 and the Generalitat Valenciana for Grants PROMETEOII/2013/005.
Type: Artículo

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