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Stereoselective binding of flurbiprofen enantiomers and their methyl esters to human serum albumin studied by time-resolved phosphoresce

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Stereoselective binding of flurbiprofen enantiomers and their methyl esters to human serum albumin studied by time-resolved phosphoresce

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Lammers, I.; Lhiaubet, VL.; Jiménez Molero, MC.; Ariese, F.; Miranda Alonso, MÁ.; Gooijer, C. (2012). Stereoselective binding of flurbiprofen enantiomers and their methyl esters to human serum albumin studied by time-resolved phosphoresce. Chirality. 24(10):840-846. doi:10.1002/chir.22080

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/70420

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Title: Stereoselective binding of flurbiprofen enantiomers and their methyl esters to human serum albumin studied by time-resolved phosphoresce
Author:
UPV Unit: Universitat Politècnica de València. Instituto Universitario Mixto de Tecnología Química - Institut Universitari Mixt de Tecnologia Química
Universitat Politècnica de València. Departamento de Química - Departament de Química
Issued date:
Abstract:
The interaction of the nonsteroidal anti-inflammatory drug flurbiprofen (FBP) with human serum albumin (HSA) hardly influences the fluorescence of the protein's single tryptophan (Trp). Therefore, in addition to fluorescence, ...[+]
Subjects: Dexter resonance energy transfer , nonlinear Stern-Volmer plot , heavy atom effect , Sudlow's binding sites
Copyrigths: Cerrado
Source:
Chirality. (issn: 0899-0042 )
DOI: 10.1002/chir.22080
Publisher:
Wiley
Publisher version: http://dx.doi.org/10.1002/chir.22080
Thanks:
This research was financed by the Netherlands Organisation for Scientific Research NWO-CW (contract number ECHO 700.55.014) and by the Spanish Government MINECO (project CTQ2010-14882). VLV's stay at LaserLaB Amsterdam was ...[+]
Type: Artículo

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