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Antineoplastic tropolone derivatives as useful biomarkers: fluorescence enhancement upon binding to biological targets

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Antineoplastic tropolone derivatives as useful biomarkers: fluorescence enhancement upon binding to biological targets

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Tormos Faus, RE.; Bosca Mayans, F. (2013). Antineoplastic tropolone derivatives as useful biomarkers: fluorescence enhancement upon binding to biological targets. RSC Advances. 3(30):12031-12034. doi:10.1039/c3ra42122h

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/71083

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Title: Antineoplastic tropolone derivatives as useful biomarkers: fluorescence enhancement upon binding to biological targets
Author:
UPV Unit: Universitat Politècnica de València. Instituto Universitario Mixto de Tecnología Química - Institut Universitari Mixt de Tecnologia Química
Universitat Politècnica de València. Departamento de Química - Departament de Química
Issued date:
Abstract:
It has been observed for the first time that the binding of tropolone derivatives to human serum albumin (HSA) produce a high fluorescence promotion. Important evidence of the immobilization of these drugs into the protein ...[+]
Subjects: HUMAN-SERUM-ALBUMIN , HINOKITIOL-RELATED COMPOUNDS , COLCHICINE , PHOTOPHYSICS , PHARMACOLOGY , INHIBITION , BOVINE , DRUG
Copyrigths: Cerrado
Source:
RSC Advances. (issn: 2046-2069 )
DOI: 10.1039/c3ra42122h
Publisher:
Royal Society of Chemistry
Publisher version: http://dx.doi.org/10.1039/c3ra42122h
Thanks:
Financial support from Spanish government (CTQ2010-19909) is gratefully acknowledged.
Type: Artículo

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