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Diffusion and Monod kinetics model to determine in vivo human corneal oxygen-consumption rate during soft contact lens wear

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Diffusion and Monod kinetics model to determine in vivo human corneal oxygen-consumption rate during soft contact lens wear

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dc.contributor.author Del Castillo, Luis Felipe es_ES
dc.contributor.author Ferreira da Silva, Ana R. es_ES
dc.contributor.author Hernández, Saúl Iván es_ES
dc.contributor.author Aguiella-Arzo, Marcelo es_ES
dc.contributor.author Balado, Andreu es_ES
dc.contributor.author Mollá Romano, Sergio es_ES
dc.contributor.author Compañ Moreno, Vicente es_ES
dc.date.accessioned 2016-10-05T10:02:18Z
dc.date.available 2016-10-05T10:02:18Z
dc.date.issued 2015-03
dc.identifier.issn 1888-4296
dc.identifier.uri http://hdl.handle.net/10251/71218
dc.description.abstract PURPOSE: We present an analysis of the corneal oxygen consumption Qc from non-linear models, using data of oxygen partial pressure or tension (P(O2) ) obtained from in vivo estimation previously reported by other authors. (1) METHODS: Assuming that the cornea is a single homogeneous layer, the oxygen permeability through the cornea will be the same regardless of the type of lens that is available on it. The obtention of the real value of the maximum oxygen consumption rate Qc,max is very important because this parameter is directly related with the gradient pressure profile into the cornea and moreover, the real corneal oxygen consumption is influenced by both anterior and posterior oxygen fluxes. RESULTS: Our calculations give different values for the maximum oxygen consumption rate Qc,max, when different oxygen pressure values (high and low P(O2)) are considered at the interface cornea-tears film. CONCLUSION: Present results are relevant for the calculation on the partial pressure of oxygen, available at different depths into the corneal tissue behind contact lenses of different oxygen transmissibility. es_ES
dc.language Inglés es_ES
dc.publisher Elsevier es_ES
dc.relation.ispartof Journal of Optometry es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Consumo de oxigeno de la cornea es_ES
dc.subject Corneal oxygen consumption es_ES
dc.subject Corneal oxygen permeability es_ES
dc.subject Corneal oxygen pressure es_ES
dc.subject Monod kinetics model es_ES
dc.subject modelo cinetico de Monod es_ES
dc.subject permeabilidad al oxigeno de la cornea es_ES
dc.subject presion del oxigeno en la cornea es_ES
dc.subject.classification MAQUINAS Y MOTORES TERMICOS es_ES
dc.subject.classification FISICA APLICADA es_ES
dc.title Diffusion and Monod kinetics model to determine in vivo human corneal oxygen-consumption rate during soft contact lens wear es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1016/j.optom.2014.06.002
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada es_ES
dc.description.bibliographicCitation Del Castillo, LF.; Ferreira Da Silva, AR.; Hernández, SI.; Aguiella-Arzo, M.; Balado, A.; Mollá Romano, S.; Compañ Moreno, V. (2015). Diffusion and Monod kinetics model to determine in vivo human corneal oxygen-consumption rate during soft contact lens wear. Journal of Optometry. 8(1):12-18. doi:10.1016/j.optom.2014.06.002 es_ES
dc.description.accrualMethod Senia es_ES
dc.relation.publisherversion http://dx.doi.org/10.1016/j.optom.2014.06.002 es_ES
dc.description.upvformatpinicio 12 es_ES
dc.description.upvformatpfin 18 es_ES
dc.type.version info:eu repo/semantics/publishedVersion es_ES
dc.description.volume 8 es_ES
dc.description.issue 1 es_ES
dc.relation.senia 282240 es_ES
dc.identifier.pmcid PMC4314625 en_EN


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