- -

MicroRNAs: Promising New Antiangiogenic Targets in Cancer

RiuNet: Institutional repository of the Polithecnic University of Valencia

Share/Send to

Cited by

Statistics

MicroRNAs: Promising New Antiangiogenic Targets in Cancer

Show simple item record

Files in this item

dc.contributor.author Gallach, Sandra es_ES
dc.contributor.author Calabuig-Farinas, Silvia es_ES
dc.contributor.author Jantus Lewintre, Eloisa es_ES
dc.contributor.author Camps, Carlos es_ES
dc.date.accessioned 2016-10-24T07:26:32Z
dc.date.available 2016-10-24T07:26:32Z
dc.date.issued 2014
dc.identifier.issn 2314-6133
dc.identifier.uri http://hdl.handle.net/10251/72641
dc.description.abstract [EN] MicroRNAs are one class of small, endogenous, non-coding RNAs that are approximately 22 nucleotides in length; they are very numerous, have been phylogenetically conserved, and involved in biological processes such as development, differentiation, cell proliferation, and apoptosis. MicroRNAs contribute to modulating the expression levels of specific proteins based on sequence complementarity with their target mRNA molecules and so they play a key role in both health and disease. Angiogenesis is the process of new blood vessel formation from preexisting ones, which is particularly relevant to cancer and its progression. Over the last few years, microRNAs have emerged as critical regulators of signalling pathways in multiple cell types including endothelial and perivascular cells. This review summarises the role of miRNAs in tumour angiogenesis and their potential implications as therapeutic targets in cancer. es_ES
dc.description.sponsorship This study was partially supported by a Grant from Ministerio de Ciencia e Inovacion de Espana (TRA09-0132), Beca Roche en Onco-Hematologia 2009, and Red Tematica de Investigacion Cooperativa en Cancer (RD12/0036/0025).
dc.language Inglés es_ES
dc.publisher Hindawi Publishing Corporation es_ES
dc.relation Ministerio de Ciencia e Inovacion de Espana TRA09-0132 es_ES
dc.relation Beca Roche en Onco-Hematologia es_ES
dc.relation Red Tematica de Investigacion Cooperativa en Cancer RD12/0036/0025 es_ES
dc.relation.ispartof BioMed Research International es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject ENDOTHELIAL GROWTH-FACTOR es_ES
dc.subject HUMAN BREAST-CANCER es_ES
dc.subject TUMOR ANGIOGENESIS es_ES
dc.subject GENE-EXPRESSION es_ES
dc.subject DOWN-REGULATION es_ES
dc.subject MIR-200 FAMILY es_ES
dc.subject NUCLEAR EXPORT es_ES
dc.subject SMALL RNAS es_ES
dc.subject IN-VIVO es_ES
dc.subject MICROPROCESSOR COMPLEX es_ES
dc.subject.classification MICROBIOLOGIA es_ES
dc.title MicroRNAs: Promising New Antiangiogenic Targets in Cancer es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1155/2014/878450
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural - Escola Tècnica Superior d'Enginyeria Agronòmica i del Medi Natural es_ES
dc.description.bibliographicCitation Gallach, S.; Calabuig-Farinas, S.; Jantus Lewintre, E.; Camps, C. (2014). MicroRNAs: Promising New Antiangiogenic Targets in Cancer. BioMed Research International. 2014. doi:10.1155/2014/878450 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://dx.doi.org/10.1155/2014/878450 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 2014 es_ES
dc.relation.senia 282058 es_ES
dc.identifier.pmid 25197665
dc.identifier.pmcid PMC4150436 en_EN
dc.contributor.funder Ministerio de Ciencia e Innovación
dc.contributor.funder Red Temática de Investigación Cooperativa en Cáncer


This item appears in the following Collection(s)

Show simple item record