dc.contributor.author |
Amr, Fares Ibrahim
|
es_ES |
dc.contributor.author |
Vila, Carlos
|
es_ES |
dc.contributor.author |
Blay, Gonzalo
|
es_ES |
dc.contributor.author |
Muñoz Roca, María del Carmen
|
es_ES |
dc.contributor.author |
Pedro, José R.
|
es_ES |
dc.date.accessioned |
2016-11-04T14:19:40Z |
|
dc.date.available |
2016-11-04T14:19:40Z |
|
dc.date.issued |
2016-05-19 |
|
dc.identifier.issn |
1615-4150 |
|
dc.identifier.uri |
http://hdl.handle.net/10251/73326 |
|
dc.description.abstract |
A quinine-derived thiourea catalysed the
enantioselective addition of 4-substituted pyrazolones
to isatin-derived ketimines, providing a variety
of aminooxindole-pyrazolone adducts containing
congested vicinal tetrasubstituted stereocentres with
excellent outcomes (up to 98% yield, >20:1 dr and
98% ee). |
es_ES |
dc.description.sponsorship |
Financial support from the MINECO (Gobierno de Espana and FEDER (EU)) (CTQ2013-47949-P) and from Generalitat Valenciana (ISIC2012/001) is gratefully acknowledged. C. V. thanks MINECO for JdC contract. Access to NMR, MS and X-ray facilities from the Servei central de support a la investigacio experimental (SCSIE)-UV is also acknowledged. |
en_EN |
dc.language |
Inglés |
es_ES |
dc.publisher |
Wiley |
es_ES |
dc.relation.ispartof |
Advanced Synthesis and Catalysis |
es_ES |
dc.rights |
Reserva de todos los derechos |
es_ES |
dc.subject |
Asymmetric catalysis |
es_ES |
dc.subject |
Isatin-derived ketimines |
es_ES |
dc.subject |
Organocatalysis |
es_ES |
dc.subject |
Pyrazolones |
es_ES |
dc.subject |
Quaternary stereocenters |
es_ES |
dc.subject.classification |
FISICA APLICADA |
es_ES |
dc.title |
Organocatalytic Enantioselective Alkylation of Pyrazol-3-ones with Isatin-Derived Ketimines: Stereocontrolled Construction of Vicinal Tetrasubstituted Stereocenters |
es_ES |
dc.type |
Artículo |
es_ES |
dc.identifier.doi |
10.1002/adsc.201600036 |
|
dc.relation.projectID |
info:eu-repo/grantAgreement/MINECO//CTQ2013-47494-P/ES/NUEVOS RETOS EN EL DESARROLLO DE PROCESOS ENANTIOSELECTIVOS DE FORMACION DE ENLACES C-C MEDIANTE CATALISIS DUAL COOPERATIVA/ |
es_ES |
dc.relation.projectID |
info:eu-repo/grantAgreement/GVA//ISIC%2F2012%2F001/ |
es_ES |
dc.rights.accessRights |
Cerrado |
es_ES |
dc.contributor.affiliation |
Universitat Politècnica de València. Departamento de Física Aplicada - Departament de Física Aplicada |
es_ES |
dc.contributor.affiliation |
Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería del Diseño - Escola Tècnica Superior d'Enginyeria del Disseny |
es_ES |
dc.description.bibliographicCitation |
Amr, FI.; Vila, C.; Blay, G.; Muñoz Roca, MDC.; Pedro, JR. (2016). Organocatalytic Enantioselective Alkylation of Pyrazol-3-ones with Isatin-Derived Ketimines: Stereocontrolled Construction of Vicinal Tetrasubstituted Stereocenters. Advanced Synthesis and Catalysis. 358(10):1583-1588. https://doi.org/10.1002/adsc.201600036 |
es_ES |
dc.description.accrualMethod |
S |
es_ES |
dc.relation.publisherversion |
http://dx.doi.org/10.1002/adsc.201600036 |
es_ES |
dc.description.upvformatpinicio |
1583 |
es_ES |
dc.description.upvformatpfin |
1588 |
es_ES |
dc.type.version |
info:eu-repo/semantics/publishedVersion |
es_ES |
dc.description.volume |
358 |
es_ES |
dc.description.issue |
10 |
es_ES |
dc.relation.senia |
316156 |
es_ES |
dc.identifier.eissn |
1615-4169 |
|
dc.contributor.funder |
Generalitat Valenciana |
es_ES |
dc.contributor.funder |
Ministerio de Economía y Competitividad |
es_ES |
dc.contributor.funder |
European Regional Development Fund |
es_ES |