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Sister chromatid exchange, (SCE), High-Frequency Cells (HFCs) and SCE distribution patterns in peripheral blood lymphocytes of Spanish adult smokers compared to non-smokers

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Sister chromatid exchange, (SCE), High-Frequency Cells (HFCs) and SCE distribution patterns in peripheral blood lymphocytes of Spanish adult smokers compared to non-smokers

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dc.contributor.author Sebastia, Natividad es_ES
dc.contributor.author Hervas, David es_ES
dc.contributor.author Almonacid, Miguel es_ES
dc.contributor.author Villaescusa, Juan Ignacio es_ES
dc.contributor.author Soriano, Jose Miguel es_ES
dc.contributor.author Sahuquillo, Vicenta es_ES
dc.contributor.author Esteban, Valentin es_ES
dc.contributor.author Barquinero, Joan Francesc es_ES
dc.contributor.author Verdú Martín, Gumersindo Jesús es_ES
dc.contributor.author Cervera, Jose es_ES
dc.contributor.author Such, Esperanza es_ES
dc.contributor.author Montoro, Alegria es_ES
dc.date.accessioned 2016-11-17T11:04:14Z
dc.date.available 2016-11-17T11:04:14Z
dc.date.issued 2014-04
dc.identifier.issn 0278-6915
dc.identifier.uri http://hdl.handle.net/10251/74276
dc.description.abstract [EN] According to the International Agency for Research on Cancer, smoking tobacco is a major cause of cancer in humans. It causes about half of all male cancer deaths and an ever increasing number of cancer deaths in females. The aim of this study was to establish whether cigarette smoking increases sister chromatid exchanges (SCEs) in peripheral blood lymphocytes in two Spanish population groups; light and heavy smokers. The mean number of High-Frequency Cells (HFCs) was determined and, the SCE distribution pattern among the chromosomes was analysed represented by a ratio described below. A local sample of 101 adult smokers (n = 48) and non-smokers (n = 53), aged from 18 to 49 years, was studied using SCE levels in peripheral lymphocytes. Heavy smoking (>= 10 cigarettes per day) increased significantly the SCE frequency and the HFC parameters. Neither age nor sex significantly influenced the frequencies in the groups studied. es_ES
dc.language Inglés es_ES
dc.publisher Elsevier es_ES
dc.relation.ispartof Food and Chemical Toxicology es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Tobacco es_ES
dc.subject Cytogenetic assessment es_ES
dc.subject Biomarker es_ES
dc.subject SCEs es_ES
dc.subject.classification INGENIERIA NUCLEAR es_ES
dc.title Sister chromatid exchange, (SCE), High-Frequency Cells (HFCs) and SCE distribution patterns in peripheral blood lymphocytes of Spanish adult smokers compared to non-smokers es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1016/j.fct.2014.01.011
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería Química y Nuclear - Departament d'Enginyeria Química i Nuclear es_ES
dc.description.bibliographicCitation Sebastia, N.; Hervas, D.; Almonacid, M.; Villaescusa, JI.; Soriano, JM.; Sahuquillo, V.; Esteban, V.... (2014). Sister chromatid exchange, (SCE), High-Frequency Cells (HFCs) and SCE distribution patterns in peripheral blood lymphocytes of Spanish adult smokers compared to non-smokers. Food and Chemical Toxicology. 66:107-112. doi:10.1016/j.fct.2014.01.011 es_ES
dc.description.accrualMethod Senia es_ES
dc.relation.publisherversion http://dx.doi.org/10.1016/j.fct.2014.01.011 es_ES
dc.description.upvformatpinicio 107 es_ES
dc.description.upvformatpfin 112 es_ES
dc.type.version info:eu repo/semantics/publishedVersion es_ES
dc.description.volume 66 es_ES
dc.relation.senia 268802 es_ES
dc.identifier.eissn 1873-6351
dc.identifier.pmid 24444548


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