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Facilitated Anion Transport Induces Hyperpolarization of the Cell Membrane That Triggers Differentiation and Cell Death in Cancer Stem Cells

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Facilitated Anion Transport Induces Hyperpolarization of the Cell Membrane That Triggers Differentiation and Cell Death in Cancer Stem Cells

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Soto-Cerrato, V.; Manuel-Manresa, P.; Hernando, E.; Calabuig-Farinas, S.; Martinez-Romero, A.; Fernandez-Dueñas, V.; Sahlholm, K.... (2015). Facilitated Anion Transport Induces Hyperpolarization of the Cell Membrane That Triggers Differentiation and Cell Death in Cancer Stem Cells. Journal of the American Chemical Society. 137(50):15892-15898. doi:10.1021/jacs.5b09970

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Title: Facilitated Anion Transport Induces Hyperpolarization of the Cell Membrane That Triggers Differentiation and Cell Death in Cancer Stem Cells
Author:
UPV Unit: Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural - Escola Tècnica Superior d'Enginyeria Agronòmica i del Medi Natural
Issued date:
Abstract:
Facilitated anion transport potentially represents a powerful tool to modulate various cellular functions. However, research into the biological effects of small molecule anionophores is still at an early stage. Here we ...[+]
Subjects: SYNTHETIC ION CHANNELS , CHLORIDE TRANSPORT , TRANSMEMBRANE TRANSPORT , PROGRESSION , BINDING , PH , APOPTOSIS , CARRIERS , ANALOGS
Copyrigths: Cerrado
Source:
Journal of the American Chemical Society. (issn: 0002-7863 )
DOI: 10.1021/jacs.5b09970
Publisher:
American Chemical Society
Publisher version: https://dx.doi.org/10.1021/jacs.5b09970
Thanks:
This work was supported by grants from the Spanish government and the EU (FIS PI13/00089, PIS PI12/02838, FIS PI12/00956 and RD12/0036/0025), a grant from La Marato de TV3 Foundation (20132730), a grant from SEPAR (17/2014), ...[+]
Type: Artículo

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