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Rats with minimal hepatic encephalopathy show reduced cGMP-dependent protein kinase activity in hypothalamus correlating with circadian rhythms alterations

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Rats with minimal hepatic encephalopathy show reduced cGMP-dependent protein kinase activity in hypothalamus correlating with circadian rhythms alterations

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Felipo, V.; Piedrafita, B.; Barios, JA.; Agustí, A.; Ahabrach, H.; Romero-Vives, M.; Barrio, LC.... (2015). Rats with minimal hepatic encephalopathy show reduced cGMP-dependent protein kinase activity in hypothalamus correlating with circadian rhythms alterations. Chronobiology International. 1-14. doi:10.3109/07420528.2015.1057640

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/79566

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Title: Rats with minimal hepatic encephalopathy show reduced cGMP-dependent protein kinase activity in hypothalamus correlating with circadian rhythms alterations
Author: Felipo, Vicente Piedrafita, Blanca Barios, Juan A. Agustí, Ana Ahabrach, Hanan Romero-Vives, María Barrio, Luis C. Rey, Beatriz Gaztelu, Jose M. Llansola, Marta
UPV Unit: Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural - Escola Tècnica Superior d'Enginyeria Agronòmica i del Medi Natural
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Abstract:
[EN] Patients with liver cirrhosis show disturbances in sleep and in its circadian rhythms which are an early sign of minimal hepatic encephalopathy (MHE). The mechanisms of these disturbances are poorly understood. Rats ...[+]
Subjects: Cyclic GMP , Electroencephalogram , Hypothalamus , Light synchronization , Porta-caval anastomosis , Sleep wake cycle
Copyrigths: Cerrado
Source:
Chronobiology International. (issn: 0742-0528 ) (eissn: 1525-6073 )
DOI: 10.3109/07420528.2015.1057640
Publisher:
Taylor & Francis
Publisher version: http://www.tandfonline.com/doi/abs/10.3109/07420528.2015.1057640
Thanks:
This study was supported by the Ministerio de Ciencia e Innovacio´n (SAF2011-23051, CSD2008-00005 and SAF2009-11614), Consellerı´a Educacio´n Generalitat Valenciana (PROMETEO-2009-027, ACOMP/2012/066, ACOMP/2013/101, ...[+]
Type: Artículo

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