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dc.contributor.author | Oroval, Mar | es_ES |
dc.contributor.author | Coronado Puchau, Marc | es_ES |
dc.contributor.author | Langer, Judith | es_ES |
dc.contributor.author | Sanz-Ortiz, Marta Norah | es_ES |
dc.contributor.author | Ribes, Àngela | es_ES |
dc.contributor.author | Aznar, Elena | es_ES |
dc.contributor.author | Coll Merino, Mª Carmen | es_ES |
dc.contributor.author | Marcos Martínez, María Dolores | es_ES |
dc.contributor.author | Sancenón Galarza, Félix | es_ES |
dc.contributor.author | Liz Marzán, Luis Manuel | es_ES |
dc.contributor.author | Martínez-Máñez, Ramón | es_ES |
dc.date.accessioned | 2017-04-11T11:32:52Z | |
dc.date.available | 2017-04-11T11:32:52Z | |
dc.date.issued | 2016-09-12 | |
dc.identifier.issn | 0947-6539 | |
dc.identifier.uri | http://hdl.handle.net/10251/79654 | |
dc.description.abstract | [EN] We present herein a novel combination of gated mesoporous silica nanoparticles (MSNs) and surface-enhanced Raman scattering (SERS) for sensing applications. As a proof-of-concept, we show the design of a system comprising MSNs loaded with crystal violet (CV), a molecule with high Raman cross section acting as SERS reporter, and capped with either a suitable DNA sequence for the detection of Mycoplasma genomic DNA or with an aptamer that selectively coordinates cocaine. In both cases the presence of the corresponding target analyte in solution (i.e., genomic DNA or cocaine) resulted in the release of CV. CV delivery was detected by SERS upon adsorption on gold nanotriangles (AuNTs), which display an efficient electromagnetic field enhancement and a high colloidal stability. By using this novel procedure a limit of detection of at least 30 copies DNA per mL was determined for the detection of Mycoplasma genomic DNA, whereas cocaine was detected at concentrations as low as 10 nm. | es_ES |
dc.description.sponsorship | M.C.-P. acknowledges an FPU Scholarship from the Spanish Ministry of Education, Culture and Sports. L.M.L.- M. acknowledges financial support from the European Research Council (ERC Advanced Grant #267867 Plasmaquo) and the European Union's Seventh Framework Programme (FP7/2007-2013 under Grant Agreement No 312184, SACS). M.O. is grateful to the Universitat Politecnica de Valencia for a FPI-UPV grant. Financial support from the Spanish Government (Project MAT2015-64139-C4-1-R MINECO/FEDER) and the Generalitat Valenciana (Project PROMETEOII/2014/047) is gratefully acknowledged. | en_EN |
dc.language | Inglés | es_ES |
dc.publisher | Wiley | es_ES |
dc.relation.ispartof | Chemistry - A European Journal | es_ES |
dc.rights | Reserva de todos los derechos | es_ES |
dc.subject.classification | QUIMICA INORGANICA | es_ES |
dc.subject.classification | QUIMICA ORGANICA | es_ES |
dc.subject.classification | QUIMICA ANALITICA | es_ES |
dc.subject.classification | INGENIERIA DE LA CONSTRUCCION | es_ES |
dc.title | Surface Enhanced Raman Scattering and Gated Materials for Sensing Applications: The Ultrasensitive Detection of Mycoplasma and Cocaine | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.1002/chem.201602457 | |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/FP7/312184/EU/Increasing Value and Flow in the Marine Biodiscovery Pipeline/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MINECO//MAT2015-64139-C4-1-R/ES/NANOMATERIALES INTELIGENTES, SONDAS Y DISPOSITIVOS PARA EL DESARROLLO INTEGRADO DE NUEVAS HERRAMIENTAS APLICADAS AL CAMPO BIOMEDICO/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/GVA//PROMETEOII%2F2014%2F047/ES/Nuevas aproximaciones para el diseño de materiales de liberación controlada y la detección de compuestos peligrosos/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/FP7/267867/EU/Development of plasmonic quorum sensors for understanding bacterial-eukaryotic cell relations/ | |
dc.rights.accessRights | Abierto | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Escuela Técnica Superior de Ingenieros Industriales - Escola Tècnica Superior d'Enginyers Industrials | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería del Diseño - Escola Tècnica Superior d'Enginyeria del Disseny | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Instituto de Reconocimiento Molecular y Desarrollo Tecnológico - Institut de Reconeixement Molecular i Desenvolupament Tecnològic | es_ES |
dc.description.bibliographicCitation | Oroval, M.; Coronado Puchau, M.; Langer, J.; Sanz-Ortiz, MN.; Ribes, À.; Aznar, E.; Coll Merino, MC.... (2016). Surface Enhanced Raman Scattering and Gated Materials for Sensing Applications: The Ultrasensitive Detection of Mycoplasma and Cocaine. Chemistry - A European Journal. 22(38):13488-13495. https://doi.org/10.1002/chem.201602457 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | http://dx.doi.org/10.1002/chem.201602457 | es_ES |
dc.description.upvformatpinicio | 13488 | es_ES |
dc.description.upvformatpfin | 13495 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 22 | es_ES |
dc.description.issue | 38 | es_ES |
dc.relation.senia | 318231 | es_ES |
dc.identifier.eissn | 1521-3765 | |
dc.contributor.funder | European Commission | |
dc.contributor.funder | European Research Council | |
dc.contributor.funder | Ministerio de Economía y Competitividad | |
dc.contributor.funder | Generalitat Valenciana | |
dc.contributor.funder | Universitat Politècnica de València |