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Pharmaceutical cost and multimorbidity with type 2 diabetes mellitus using electronic health record data

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Pharmaceutical cost and multimorbidity with type 2 diabetes mellitus using electronic health record data

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dc.contributor.author Sancho Mestre, Carla es_ES
dc.contributor.author Vivas Consuelo, David José Juan es_ES
dc.contributor.author Alvis, Luis es_ES
dc.contributor.author Romero, Martin es_ES
dc.contributor.author Usó Talamantes, Ruth es_ES
dc.contributor.author Caballer Tarazona, Vicent es_ES
dc.date.accessioned 2017-05-10T14:25:24Z
dc.date.available 2017-05-10T14:25:24Z
dc.date.issued 2016
dc.identifier.issn 1472-6963
dc.identifier.uri http://hdl.handle.net/10251/80834
dc.description © 2016 The Author(s). Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. es_ES
dc.description.abstract [EN] Background: The objective of the study is to estimate the frequency of multimorbidity in type 2 diabetes patients classified by health statuses in a European region and to determine the impact on pharmaceutical expenditure. Methods: Cross-sectional study of the inhabitants of a southeastern European region with a population of 5,150,054, using data extracted from Electronic Health Records for 2012. 491,854 diabetic individuals were identified and selected through clinical codes, Clinical Risk Groups and diabetes treatment and/or blood glucose reagent strips. Patients with type 1 diabetes and gestational diabetes were excluded. All measurements were obtained at individual level. The prevalence of common chronic diseases and co-occurrence of diseases was established using factorial analysis. Results: The estimated prevalence of diabetes was 9.6 %, with nearly 70 % of diabetic patients suffering from more than two comorbidities. The most frequent of these was hypertension, which for the groups of patients in Clinical Risk Groups (CRG) 6 and 7 was 84.3 % and 97.1 % respectively. Regarding age, elderly patients have more probability of suffering complications than younger people. Moreover, women suffer complications more frequently than men, except for retinopathy, which is more common in males. The highest use of insulins, oral antidiabetics (OAD) and combinations was found in diabetic patients who also suffered cardiovascular disease and neoplasms. The average cost for insulin was 153€ and that of OADs 306€. Regarding total pharmaceutical cost, the greatest consumers were patients with comorbidities of respiratory illness and neoplasms, with respective average costs of 2,034.2€ and 1,886.9€. Conclusions: Diabetes is characterized by the co-occurrence of other diseases, which has implications for disease management and leads to a considerable increase in consumption of medicines for this pathology and, as such, pharmaceutical expenditure. es_ES
dc.description.sponsorship This study was financed by a grant from the Fondo de Investigaciones de la Seguridad Social Instituto de Salud Carlos III, the Spanish Ministry of Health (FIS PI12/0037). en_EN
dc.language Inglés es_ES
dc.publisher BioMed Central es_ES
dc.relation.ispartof BMC Health Services Research es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject Diabetes mellitus es_ES
dc.subject Pharmaceutical expenditure es_ES
dc.subject Multiborbidity es_ES
dc.subject.classification ECONOMIA APLICADA es_ES
dc.title Pharmaceutical cost and multimorbidity with type 2 diabetes mellitus using electronic health record data es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1186/s12913-016-1649-2
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//PI12%2F00037/ES/Análisis y modelización del gasto farmacéutico utilizando Clinical Risk Group/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Facultad de Administración y Dirección de Empresas - Facultat d'Administració i Direcció d'Empreses es_ES
dc.description.bibliographicCitation Sancho Mestre, C.; Vivas Consuelo, DJJ.; Alvis, L.; Romero, M.; Usó Talamantes, R.; Caballer Tarazona, V. (2016). Pharmaceutical cost and multimorbidity with type 2 diabetes mellitus using electronic health record data. BMC Health Services Research. 16(394):1-8. https://doi.org/10.1186/s12913-016-1649-2 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://dx.doi.org/10.1186/s12913-016-1649-2 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 8 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 16 es_ES
dc.description.issue 394 es_ES
dc.relation.senia 316256 es_ES
dc.identifier.pmid 27534391 en_EN
dc.identifier.pmcid PMC4989292 en_EN
dc.contributor.funder Ministerio de Economía y Competitividad es_ES
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