- -

Variability in mutational fitness effects prevents full lethal transitions in large quasispecies populations

RiuNet: Repositorio Institucional de la Universidad Politécnica de Valencia

Compartir/Enviar a

Citas

Estadísticas

Variability in mutational fitness effects prevents full lethal transitions in large quasispecies populations

Mostrar el registro completo del ítem

Sardanyes Cayuela, J.; Simó, C.; Martínez, R.; Solé, RV.; Elena Fito, SF. (2014). Variability in mutational fitness effects prevents full lethal transitions in large quasispecies populations. Scientific Reports. (4):1-9. doi:10.1038/srep04625

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/81389

Ficheros en el ítem

Metadatos del ítem

Título: Variability in mutational fitness effects prevents full lethal transitions in large quasispecies populations
Autor:
Entidad UPV: Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes
Fecha difusión:
Resumen:
[EN] The distribution of mutational fitness effects (DMFE) is crucial to the evolutionary fate of quasispecies. In this article we analyze the effect of the DMFE on the dynamics of a large quasispecies by means of a ...[+]
Palabras clave: Single-nucleotide substitutions , Immunodeficiency-virus type-1 , Vesicular stomatitis-virus , Tobacco-ETCH-virus , Error threshold , RNA virus , Deleterious mutations , Muller ratchet , Human cancers , Evolution
Derechos de uso: Reconocimiento - Sin obra derivada - No comercial (by-nd-nc)
Fuente:
Scientific Reports. (issn: 2045-2322 )
DOI: 10.1038/srep04625
Editorial:
Nature Publishing Group
Versión del editor: http://doi.org/10.1038/srep04625
Agradecimientos:
We thank the members of the Complex Systems Lab as well as Phillip Gerrish, Susanna C. Manrubia, and Ernest Fontich for their helpful comments. The authors acknowledge the computing facilities of the Dynamical Systems Group ...[+]
Tipo: Artículo

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro completo del ítem