- -

Gd-Si Oxide Nanoparticles as Contrast Agents in Magnetic Resonance Imaging

RiuNet: Institutional repository of the Polithecnic University of Valencia

Share/Send to

Cited by

Statistics

Gd-Si Oxide Nanoparticles as Contrast Agents in Magnetic Resonance Imaging

Show simple item record

Files in this item

dc.contributor.author Cabrera-García, Alejandro es_ES
dc.contributor.author Vidal Moya, José Alejandro es_ES
dc.contributor.author Bernabéu, Ángela es_ES
dc.contributor.author Pacheco Torres, Jesús es_ES
dc.contributor.author Checa Chavarría, Elisa es_ES
dc.contributor.author Fernández, Eduardo es_ES
dc.contributor.author Botella Asuncion, Pablo es_ES
dc.date.accessioned 2017-05-24T06:25:05Z
dc.date.available 2017-05-24T06:25:05Z
dc.date.issued 2016-06
dc.identifier.issn 2079-4991
dc.identifier.uri http://hdl.handle.net/10251/81698
dc.description.abstract [EN] We describe the synthesis, characterization and application as contrast agents in magnetic resonance imaging of a novel type of magnetic nanoparticle based on Gd-Si oxide, which presents high Gd3+ atom density. For this purpose, we have used a Prussian Blue analogue as the sacrificial template by reacting with soluble silicate, obtaining particles with nanorod morphology and of small size (75 nm). These nanoparticles present good biocompatibility and higher longitudinal and transversal relaxivity values than commercial Gd3+ solutions, which significantly improves the sensitivity of in vivo magnetic resonance images. es_ES
dc.description.sponsorship The authors thank the Spanish MINECO (projects MAT2012-39290-CO2-01 and MAT2012-39290-CO2-02) for financial support. A.C.-G. also thanks "La Caixa" Foundation for a Ph.D. scholarship. We fully appreciate the assistance of the Electron Microscopy Service of the UPV and INSCANNER S.L. en_EN
dc.language Inglés es_ES
dc.publisher MDPI es_ES
dc.relation info:eu-repo/grantAgreement/MINECO//MAT2012-39290-C02-01/ES/OPTIMIZACION FUNCIONAL Y MEJORA DE LA BIOCOMPATIBILIDAD A LARGO PLAZO DE ELECTRODOS NEURALES/ es_ES
dc.relation MINECO/MAT2012-39290-C02-C02
dc.relation.ispartof Nanomaterials es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Prussian Blue analogues es_ES
dc.subject Gd-Si nanoparticles es_ES
dc.subject Magnetic resonance imaging es_ES
dc.subject Contrast agent es_ES
dc.subject Electron Microscopy Service of the UPV
dc.title Gd-Si Oxide Nanoparticles as Contrast Agents in Magnetic Resonance Imaging es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.3390/nano6060109
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto Universitario Mixto de Tecnología Química - Institut Universitari Mixt de Tecnologia Química es_ES
dc.description.bibliographicCitation Cabrera-García, A.; Vidal Moya, JA.; Bernabéu, Á.; Pacheco Torres, J.; Checa Chavarría, E.; Fernández, E.; Botella Asuncion, P. (2016). Gd-Si Oxide Nanoparticles as Contrast Agents in Magnetic Resonance Imaging. Nanomaterials. 6(6):1-15. https://doi.org/10.3390/nano6060109 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://doi.org/10.3390/nano6060109 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 15 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 6 es_ES
dc.description.issue 6 es_ES
dc.relation.senia 334946 es_ES
dc.identifier.pmid 28335240 en_EN
dc.identifier.pmcid PMC5302615 en_EN
dc.contributor.funder Ministerio de Economía, Industria y Competitividad


This item appears in the following Collection(s)

Show simple item record