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The transcriptional regulator BBX24 impairs DELLA activity to promote shade avoidance in Arabidopsis thaliana

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The transcriptional regulator BBX24 impairs DELLA activity to promote shade avoidance in Arabidopsis thaliana

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dc.contributor.author Crocco, CD es_ES
dc.contributor.author Locascio ., Antonella Anna Maria es_ES
dc.contributor.author Escudero, Cristian M. es_ES
dc.contributor.author Alabadí Diego, David es_ES
dc.contributor.author Blazquez Rodriguez, Miguel Angel es_ES
dc.contributor.author Botto, JF es_ES
dc.date.accessioned 2017-05-29T07:00:46Z
dc.date.available 2017-05-29T07:00:46Z
dc.date.issued 2015-02
dc.identifier.issn 2041-1723
dc.identifier.uri http://hdl.handle.net/10251/81867
dc.description.abstract [EN] In response to canopy shade, plant vegetative structures elongate to gain access to light. However, the mechanism that allows a plastic transcriptional response to canopy shade light is not fully elucidated. Here we propose that the activity of PIF4, a key transcription factor in the shade signalling network, is modulated by the interplay between the BBX24 transcriptional regulator and DELLA proteins, which are negative regulators of the gibberellin (GA) signalling pathway. We show that GA-related targets are enriched among genes responsive to BBX24 under shade and that the shade-response defect in bbx24 mutants is rescued by a GA treatment that promotes DELLA degradation. BBX24 physically interacts with DELLA proteins and alleviates DELLA-mediated repression of PIF4 activity. The proposed molecular mechanism provides reversible regulation of the activity of a key transcription factor that may prove especially relevant under fluctuating light conditions. es_ES
dc.description.sponsorship We thank Santiago Mora Garcia for valuable initial discussions and Peter Quail for the PIL1::LUC construct. This work was supported by grants from Agencia Nacional de Promocion Cientifica y Tecnologica, and Universidad de Buenos Aires (to J.F.B), and the Spanish Ministry of Science, BIO2010-15071 (to M.A.B.). en_EN
dc.language Inglés es_ES
dc.publisher Nature Publishing Group es_ES
dc.relation.ispartof Nature Communications es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject B-Box protein es_ES
dc.subject Cell elongation es_ES
dc.subject Functional genomics es_ES
dc.subject Signaling pathways es_ES
dc.subject Plant-responses es_ES
dc.subject DNA-binding es_ES
dc.subject Gibberellin es_ES
dc.subject Light es_ES
dc.subject Growth es_ES
dc.subject Photomorphogenesis es_ES
dc.title The transcriptional regulator BBX24 impairs DELLA activity to promote shade avoidance in Arabidopsis thaliana es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1038/ncomms7202
dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/644435/EU/Evaluation of Plant Signaling Networks in Natural Environments/ en_EN
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes es_ES
dc.description.bibliographicCitation Crocco, C.; Locascio ., AAM.; Escudero, CM.; Alabadí Diego, D.; Blazquez Rodriguez, MA.; Botto, J. (2015). The transcriptional regulator BBX24 impairs DELLA activity to promote shade avoidance in Arabidopsis thaliana. Nature Communications. 6:1-10. https://doi.org/10.1038/ncomms7202 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://doi.org/10.1038/ncomms7202 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 10 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 6 es_ES
dc.relation.senia 307532 es_ES
dc.identifier.pmid 25656233
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