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Disc-based microarrays: principles and analytical applications

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Disc-based microarrays: principles and analytical applications

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dc.contributor.author Morais, Sergi es_ES
dc.contributor.author Puchades, Rosa es_ES
dc.contributor.author Maquieira Catala, Ángel es_ES
dc.date.accessioned 2017-06-15T11:18:20Z
dc.date.available 2017-06-15T11:18:20Z
dc.date.issued 2016-07
dc.identifier.issn 1618-2642
dc.identifier.uri http://hdl.handle.net/10251/82885
dc.description.abstract [EN] The idea of using disk drives to monitor molecular biorecognition events on regular optical discs has received considerable attention during the last decade. CDs, DVDs, Blu-ray discs and other new optical discs are universal and versatile supports with the potential for development of protein and DNA microarrays. Besides, standard disk drives incorporated in personal computers can be used as compact and affordable optical reading devices. Consequently, a CD technology, resulting from the audio-video industry, has been used to develop analytical applications in health care, environmental monitoring, food safety and quality assurance. The review presents and critically evaluates the current state of the art of disc-based microarrays with illustrative examples, including past, current and future developments. Special mention is made of the analytical developments that use either chemically activated or raw standard CDs where proteins, oligonucleotides, peptides, haptens or other biological probes are immobilized. The discs are also used to perform the assays and must maintain their readability with standard optical drives. The concept and principle of evolving disc-based microarrays and the evolution of disk drives as optical detectors are also described. The review concludes with the most relevant uses ordered chronologically to provide an overview of the progress of CD technology applications in the life sciences. Also, it provides a selection of important references to the current literature. es_ES
dc.description.sponsorship This work was supported by the Spanish Ministry of Economy and Competitiveness (project CTQ2013-45875-R) and Generalitat Valenciana (PROMETEO II 2014/040 and ACOMP 2012/158). All authors were partially sponsored by the European Regional Development Fund.
dc.language Inglés es_ES
dc.publisher Springer Verlag (Germany) es_ES
dc.relation MINECO/CTQ2013-45875-R es_ES
dc.relation GV/PROMETEO II/2014/040 es_ES
dc.relation GV/ACOMP2012/158
dc.relation.ispartof Analytical and Bioanalytical Chemistry es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Consumer electronics es_ES
dc.subject Compact disc es_ES
dc.subject Biosensing es_ES
dc.subject Molecular recognition es_ES
dc.subject Point of care es_ES
dc.subject.classification QUIMICA ANALITICA es_ES
dc.title Disc-based microarrays: principles and analytical applications es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1007/s00216-016-9423-1
dc.rights.accessRights Cerrado es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto de Reconocimiento Molecular y Desarrollo Tecnológico - Institut de Reconeixement Molecular i Desenvolupament Tecnològic es_ES
dc.contributor.affiliation Universitat Politècnica de València. Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural - Escola Tècnica Superior d'Enginyeria Agronòmica i del Medi Natural es_ES
dc.description.bibliographicCitation Morais, S.; Puchades, R.; Maquieira Catala, Á. (2016). Disc-based microarrays: principles and analytical applications. Analytical and Bioanalytical Chemistry. 408(17):4523-4534. doi:10.1007/s00216-016-9423-1 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://doi.org/10.1007/s00216-016-9423-1 es_ES
dc.description.upvformatpinicio 4523 es_ES
dc.description.upvformatpfin 4534 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 408 es_ES
dc.description.issue 17 es_ES
dc.relation.senia 314345 es_ES
dc.identifier.eissn 1618-2650
dc.identifier.pmid 26922341
dc.contributor.funder Ministerio de Economía y Competitividad
dc.contributor.funder Generalitat Valenciana
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