- -

Medically Biodegradable Hydrogenated Amorphous Silicon Microspheres

RiuNet: Institutional repository of the Polithecnic University of Valencia

Share/Send to

Cited by

Statistics

Medically Biodegradable Hydrogenated Amorphous Silicon Microspheres

Show simple item record

Files in this item

dc.contributor.author Shabir, Q. es_ES
dc.contributor.author Pokale, A. es_ES
dc.contributor.author Loni, A. es_ES
dc.contributor.author Johnson, D. R. es_ES
dc.contributor.author Canham, L.T. es_ES
dc.contributor.author Fenollosa Esteve, Roberto es_ES
dc.contributor.author Tymczenko, Michal Konrad es_ES
dc.contributor.author Rodríguez, Marie-Isabelle es_ES
dc.contributor.author Meseguer Rico, Francisco Javier es_ES
dc.contributor.author Cros, Ana es_ES
dc.contributor.author Cantarero, Andrés es_ES
dc.date.accessioned 2017-07-03T11:12:01Z
dc.date.available 2017-07-03T11:12:01Z
dc.date.issued 2011-10
dc.identifier.issn 1876-990X
dc.identifier.uri http://hdl.handle.net/10251/84338
dc.description.abstract [EN] Hydrogenated amorphous silicon colloids of low surface area (<5 m(2)/g) are shown to exhibit complete in-vitro biodegradation into orthosilicic acid within 10-15 days at 37 degrees C. When converted into polycrystalline silicon colloids, by high temperature annealing in an inert atmosphere, microparticle solubility is dramatically reduced. The data suggests that amorphous silicon does not require nanoscale porosification for full in-vivo biodegradability. This has significant implications for using a-Si:H coatings for medical implants in general, and orthopedic implants in particular. The high sphericity and biodegradability of submicron particles may also confer advantages with regards to contrast agents for medical imaging. es_ES
dc.description.sponsorship This work has been partially supported by the Spanish CICyT projects, FIS2009-07812, Consolider CSD2007-046, MAT2009-010350 and PROMETEO/2010/043. en_EN
dc.language Inglés es_ES
dc.publisher Springer Verlag (Germany) es_ES
dc.relation CICyT [FIS2009-07812] [Consolider CSD2007-046] [MAT2009-010350] es_ES
dc.relation Generalitat Valenciana [PROMETEO/2010/043] es_ES
dc.relation.ispartof Silicon es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Silicon es_ES
dc.subject Amorphous. es_ES
dc.subject Biodegradable es_ES
dc.subject Medical es_ES
dc.title Medically Biodegradable Hydrogenated Amorphous Silicon Microspheres es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1007/s12633-011-9097-4
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto Universitario Mixto de Tecnología Química - Institut Universitari Mixt de Tecnologia Química es_ES
dc.contributor.affiliation Universitat Politècnica de València. Centro de Tecnologías Físicas: Acústica, Materiales y Astrofísica - Centre de Tecnologies Físiques: Acústica, Materials i Astrofísica es_ES
dc.description.bibliographicCitation Shabir, Q.; Pokale, A.; Loni, A.; Johnson, DR.; Canham, L.; Fenollosa Esteve, R.; Tymczenko, MK.... (2011). Medically Biodegradable Hydrogenated Amorphous Silicon Microspheres. Silicon. 3(4):173-176. doi:10.1007/s12633-011-9097-4 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://doi.org/10.1007/s12633-011-9097-4 es_ES
dc.description.upvformatpinicio 173 es_ES
dc.description.upvformatpfin 176 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 3 es_ES
dc.description.issue 4 es_ES
dc.relation.senia 260972 es_ES
dc.relation.references Salonen J, Kaukonen AM, Hirvonen J, Lehto VP (2008) J Pharmaceutics 97:632–53 es_ES
dc.relation.references Anglin EJ, Cheng L, Freeman WR, Sailor MJ (2008) Adv Drug Deliv Rev 60:1266–77 es_ES
dc.relation.references O’Farrell N, Houlton A, Horrocks BR (2006) Int J Nanomedicine 1:451–72 es_ES
dc.relation.references Canham LT (1995) Adv Mater 7:1037, PCT patent WO 97/06101,1999 es_ES
dc.relation.references Park JH, Gui L, Malzahn G, Ruoslahti E, Bhatia SN, Sailor MJ (2009) Nature Mater 8:331–6 es_ES
dc.relation.references Cullis AG, Canham LT, Calcott PDJ (1997) J Appl Phys 82:909–66 es_ES
dc.relation.references Canham LT, Reeves CR (1996) Mat Res Soc Symp 414:189–90 es_ES
dc.relation.references Edell DJ, Toi VV, McNeil VM, Clark LD (1992) IEEE Trans Biomed Eng 39:635–43 es_ES
dc.relation.references Fenollosa R, Meseguer F, Tymczenko M (2008) Adv Mater 20:95 es_ES
dc.relation.references Fenollosa R, Meseguer F, Tymczenko M, Spanish Patent P200701681, 2007 es_ES
dc.relation.references Pell LE, Schricker AD, Mikulec FV, Korgel BA (2004) Langmuir 20:6546 es_ES
dc.relation.references Xifré-Perez E, Fenollosa R, Meseguer F (2011) Opt Express 19:3455–63 es_ES
dc.relation.references Fenollosa R, Ramiro-Manzano F, Tymczenko M, Meseguer F (2010) J Mater Chem 20:5210 es_ES
dc.relation.references Xifré-Pérez E, Domenech JD, Fenollosa R, Muñoz P, Capmany J, Meseguer F (2011) Opt Express 19–4:3185–92 es_ES
dc.relation.references Rodriguez I, Fenollosa R, Meseguer F, Cosmetics & Toiletries 2010;42–49 es_ES
dc.relation.references Ramiro-Manzano F, Fenollosa R, Xifré-Pérez E, Garín M, Meseguer F (2011) Adv Mater 23:3022–3025. doi: 10.1002/adma.201100986 es_ES
dc.relation.references Iler RK (1979) Chemistry of silica: solubility, polymerization, colloid & surface properties & biochemistry. Wiley, New York es_ES
dc.relation.references Tanaka K, Maruyama E, Shimado T, Okamoto H (1999) Amorphous silicon. Wiley, New York, NY es_ES
dc.relation.references Patterson AL (1939) Phys Rev 56:978–82 es_ES
dc.relation.references Canham LT, Reeves CL, King DO, Branfield PJ, Gabb JG, Ward MC (1996) Adv Mater 8:850–2 es_ES
dc.relation.references Iler RK In: Chemistry of silica: solubility, polymerization, colloid & surface properties &Biochemistry. Wiley, New York, NY es_ES
dc.relation.references Finnie KS, Waller DJ, Perret FL, Krause-Heuer AM, Lin HQ, Hanna JV, Barbe CJ (2009) J Sol-Gel Technol 49:12–8 es_ES
dc.relation.references Zhao D, Huo Q, Feng J, Chmelka BF, Stucky GD (1998) J Am Chem Soc 120:6024–36 es_ES
dc.relation.references Fan D, Akkaraju GR, Couch EF, Canham LT, Coffer JL (2010) Nanoscale 1:354–61 es_ES
dc.relation.references Tasciotti E, Godin B, Martinez JO, Chiappini C, Bhavane R, Liu X, Ferrari M (2011) Mol Imaging 10:56–8 es_ES


This item appears in the following Collection(s)

Show simple item record