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Technical Note: FIELD STUDY OF SAFETY AND ANTIBODY PRODUCTION FURTHER TO A COMBINED MYXOMATOSIS AND VIRAL HAEMORRHAGIC DISEASE (VHD) VACCINATION IN DWARF RABBITS BY INTRADERMAL ROUTE

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Technical Note: FIELD STUDY OF SAFETY AND ANTIBODY PRODUCTION FURTHER TO A COMBINED MYXOMATOSIS AND VIRAL HAEMORRHAGIC DISEASE (VHD) VACCINATION IN DWARF RABBITS BY INTRADERMAL ROUTE

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dc.contributor.author Lemière, S.
dc.contributor.author Alaphilippe, A.
dc.contributor.author Boucher, S.
dc.contributor.author Bertagnoli, S.
dc.date.accessioned 2011-02-23T16:33:03Z
dc.date.available 2011-02-23T16:33:03Z
dc.date.issued 2003
dc.identifier.issn 1257-5011
dc.identifier.uri http://hdl.handle.net/10251/9960
dc.description.abstract [EN] A study of safety of combined vaccination against myxomatosis and VHD was performed using a duly reconstituted vaccine made of a live homologous myxomatosis component SG33 strain and of an inactivated VHD component in adjuvant AG88 strain. The vaccine was administered intradermally to a representative sample of pet rabbits. A local reaction at the vaccine administration area was frequently observed from 2 to 3 days after vaccination in young animals. These local reactions were less frequently observed in adults. The reaction consisted of a local rash which usually disappeared 2 to 3 days after vaccination (maximum 1 week). The immune response following vaccination was monitored by antibody production against VHD and myxomatosis using, for the VHD vaccine component, an IHA titration method, and, for myxomatosis component, an ELISA titration method. Antibody production after vaccination was observed for both components. Maximum VHD IHA titre (192 ± 130) was obtained in vaccinated animals one month after vaccine administration. Antibodies were still detected in these animals one month later (94 ± 39). Mean titre obtained in unvaccinated controls was equal to 0. Maximum myxomatosis ELISA titre (10518 ± 2417) was obtained two months after vaccine administration. Mean titre obtained at the same time in unvaccinated controls was close to 0 (889 ± 744). es_ES
dc.language Inglés es_ES
dc.publisher World Rabbit Science. ICTA. UPV es_ES
dc.relation.ispartof World Rabbit Science
dc.rights Reserva de todos los derechos es_ES
dc.subject Myxomatosis es_ES
dc.subject Vhd es_ES
dc.subject Combined vaccine es_ES
dc.subject Intradermal route es_ES
dc.subject Syringe es_ES
dc.subject Safety es_ES
dc.subject Antibody production es_ES
dc.title Technical Note: FIELD STUDY OF SAFETY AND ANTIBODY PRODUCTION FURTHER TO A COMBINED MYXOMATOSIS AND VIRAL HAEMORRHAGIC DISEASE (VHD) VACCINATION IN DWARF RABBITS BY INTRADERMAL ROUTE es_ES
dc.type Artículo es_ES
dc.date.updated 2011-02-23T11:20:48Z
dc.identifier.doi 10.4995/wrs.2003.496
dc.rights.accessRights Abierto es_ES
dc.description.bibliographicCitation Lemière, S.; Alaphilippe, A.; Boucher, S.; Bertagnoli, S. (2003). Technical Note: FIELD STUDY OF SAFETY AND ANTIBODY PRODUCTION FURTHER TO A COMBINED MYXOMATOSIS AND VIRAL HAEMORRHAGIC DISEASE (VHD) VACCINATION IN DWARF RABBITS BY INTRADERMAL ROUTE. World Rabbit Science. 11(1):41-47. doi:10.4995/wrs.2003.496 es_ES
dc.description.accrualMethod SWORD es_ES
dc.relation.publisherversion https://doi.org/10.4995/wrs.2003.496
dc.description.upvformatpinicio 41
dc.description.upvformatpfin 47
dc.description.volume 11
dc.description.issue 1
dc.identifier.eissn 1989-8886 es_ES


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