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Browsing by Author "Gómez Ribelles, José Luís"

Now showing items 1-20 of 238

3D Culture o Multiple Myeloma Cell Line Using Microgel Environments

Marin Paya, Juan Carlos (Universitat Politècnica de València, 2021-06-03)

[ES] El mieloma múltiple es una neoplasia hematológica caracterizada por una expansión descontrolada de células plasmáticas monoclonales (mPCs) en medula ósea que producen, en la mayoría de los casos, un componente monoclonal ...
A cell-free approach with a supporting biomaterial in the form of dispersed microspheres induces hyaline cartilage formation in a rabbit knee model

Zurriaga Carda, Javier; Lastra, Maria L.; Antolinos-Turpin, Carmen M.; Morales-Román, Rosa M.; Sancho-Tello, María; Perea-Ruiz, Sofía; Milián, Lara; Fernández, Juan M.; Cortizo, Ana M.; Carda, Carmen; Gallego-Ferrer, Gloria; Gómez Ribelles, José Luís (John Wiley & Sons, 2020-05)

[EN] The objective of this study was to test a regenerative medicine strategy for the regeneration of articular cartilage. This approach combines microfracture of the subchondral bone with the implant at the site of the ...
A Definition of Dynamically Accessible Volume for Thermal Systems

Molina Mateo, José; Meseguer Dueñas, José María; Gómez Ribelles, José Luís (John Wiley & Sons, 2006-01-16)

[EN] The glass transition and physical aging processes of a polymeric material have been simulated using the bond fluctuation model. Two potentials that represent intra- and inter-molecular interactions have been employed. ...
A new waterborne chitosan-based polyurethane hydrogel as a vehicle to transplant bone marrow mesenchymal cells improved wound healing of ulcers in a diabetic rat model

Viezzer, Christian; Mazzuca, Rafael; Machado, Denise Cantarelli; Forte, María Magdalena de Camargo; Gómez Ribelles, José Luís (Elsevier, 2020-03-01)

[EN] Foot ulcers, a common complication of diabetes, can cause physical incapacity and are derived from several factors, including poor wound healing. New therapeutic strategies are needed to minimize this complication for ...
A simple model for cooperative and non-exponential processes in non-crystalline polymers

Torregrosa Cabanilles, Constantino; Molina Mateo, José; Meseguer Dueñas, José María; Gómez Ribelles, José Luís (Elsevier, 2011-01-15)

A quite simple Markov chain model is presented in an attempt to understand several characteristic properties of the structural relaxation in glass-former materials. A second order Markov model is proposed for a small region ...
A study of some fundamental physicochemical variables on the morphology of mesoporous silica nanoparticles MCM-41 type

Beltrán-Osuna, A.A.; Gómez Ribelles, José Luís; Perilla-Perilla, Jairo Ernesto (Springer-Verlag, 2017)

[EN] All variables affecting the morphology of mesoporous silica nanoparticles (MSN) should be carefully analyzed in order to truly tailored design their mesoporous structure according to their final use. Although complete ...
Adipose tissue derived stromal cells in a gelatin-based 3D matrix with exclusive ascorbic acid signalling emerged as a novel neural tissue engineering construct: an innovative prototype for soft tissue

Martin, Catherine Ann; Radhakrishnan, Subathra; Gómez Ribelles, José Luís; Trentz, Omana Anna; Nivethaa, E.A.K.; Reddy, Mettu Srinivas; Rela, Mohamed; Subbaraya, Narayana Kalkura (Oxford University Press, 2022-04-08)

[EN] The current study investigated a triad, which comprises of adipose tissue derived stem cells isolated from infrapatellar fat pad and gelatin/polyvinyl alcohol (PVA)-based matrix with exclusive ascorbic acid signalling. ...
An experimental fatigue study of a porous scaffold for the regeneration of articular cartilage

Vikingsson, Line Karina Alva; Gómez-Tejedor, José Antonio; Gallego-Ferrer, Gloria; Gómez Ribelles, José Luís (Elsevier, 2015-05-01)

The aim of this experimental study is to predict the long-term mechanical behavior of a porous scaffold implanted in a cartilage defect for tissue engineering purpose. Fatigue studies were performed by up to 100,000 ...
An experimental model to mimic the mechanical behavior of a scaffold in a cartilage defect

Vikingsson, Line Karina Alva (Universitat Politècnica de València, 2015-07-29)

[EN] Abstract The main purpose of this thesis is the design and characterization of an experimental articular cartilage model. The in vitro model is composed of a macro and micro- porous Polycaprolactone scaffold with ...
An in vitro experimental model to predict the mechanical behaviour of macroporous scaffolds implanted in articular cartilage

Vikingsson, Line Karina Alva; Gallego-Ferrer, Gloria; Gómez-Tejedor, José Antonio; Gómez Ribelles, José Luís (Elsevier, 2014-04)

A model is proposed to assess mechanical behaviour of tissue engineering scaffolds and predict their performance in vivo during tissue regeneration. To simulate the growth of tissue inside the pores of the scaffold, the ...
An innovative bioresorbable gelatin based 3D scaffold that maintains the stemness of adipose tissue derived stem cells and the plasticity of differentiated neurons

Martin, Catherine Ann; Radhakrishnan, Subathra; Nagarajan, Sakthivel; Muthukoori, Shanthini; Meseguer Dueñas, José María; Gómez Ribelles, José Luís; Lakshmi, Baddrireddi Subhadra; Nivethaa, E. A. K.; Gómez-Tejedor, José-Antonio; Reddy, Mettu Srinivas; Sellathamby, Shanmugaapriya; Rela, Mohamed; Subbaraya, Narayana Kalkura (The Royal Society of Chemistry, 2019)

[EN] Neural tissue engineering aims at producing a simulated environment using a matrix that is suitable to grow specialized neurons/glial cells pertaining to CNS/PNS which replace damaged or lost tissues. The primary goal ...
Análisis del rendimiento termodinámico de los posibles refrigerantes y ciclos alternativos para la recuperación y mejora del calor residual.

Vidal Beneito, Ana (Universitat Politècnica de València, 2020-12-09)

[ES] En la actualidad el uso eficiente de la energía y la reducción de las emisiones de gases de efecto invernadero son dos de las piedras angulares para conseguir los objetivos de desarrollo sostenible del plantea. El ...
Antibacterial topographical cues on titanium surfaces to reduce infection of bone implants

Gilabert Chirivella, Eduardo (Universitat Politècnica de València, 2015-11-10)

Proyecto confidencial (Riunet)
Antifouling zwitterionic pSBMA-MSN particles for biomedical applications

Beltrán-Osuna, A.A.; Ródenas Rochina, Joaquín; Gómez Ribelles, José Luís; Perilla-Perilla, Jairo Ernesto (John Wiley & Sons, 2019-03)

[EN] Mesoporous silica nanoparticles (MSNs) are one of the most promising nanocarriers in biomedicine. Nonetheless, surface modification has been pointed out as a condition necessary for drug delivery applications, where ...
Assessment of Parameters Influencing fiber characteristics of chitosan nanofiber membrane to optimize fiber mat productioi

Areias, A.C.; Gómez-Tejedor, José Antonio; Sencadas, V.; Alio, J.; Gómez Ribelles, José Luís; Lanceros-Mendez, S. (Wiley, 2012-06)

Electrospun chitosan nanofiber mats have been obtained using chitosan solutions in a mixture of trifluoroacetic acid and dichloromethane. The relationship between processing parameters (solvent composition, polymer ...
Assessment of parameters influencing fiber characteristics of electrospun Poly(ethyl methacrylate) scaffolds

Gómez-Tejedor, José Antonio; Van Overberghe, Niek; Rico Tortosa, Patricia María; Gómez Ribelles, José Luís (Elsevier, 2011)

This work evaluates the influence of electrospinning process parameters on the mean diameter and standard deviation of fiber diameters in electrospun poly(ethyl methacrylate) (PEMA). Processing conditions were selected ...
Biodegradable chitosan-poly(epsilon-caprolactone) dialdehyde copolymer networks for soft tissue engineering

Gámiz González, Mª Amparo; Vidaurre, Ana; Gómez Ribelles, José Luís (Elsevier, 2017)

[EN] Chitosan/PCL block-copolymer networks were synthesized using different amounts of aldehyde end capped polycaprolactone as crosslinking agent. The crosslinking reaction was performed by dissolving both components in ...
Biodegradable hydrogels based on water-soluble chitosan for cell transplant

Gámiz González, Mª Amparo (Universitat Politècnica de València, 2016-11-02)

[EN] The aim of tissue engineering is to develop functional biological substitutes to replace or restore damaged tissues by preparing three-dimensional scaffolds able to accommodate cells plus signaling factors to promote ...
Biodegradable poly(L-lactide) and polycaprolactone block copolymer networks

Escobar Ivirico, Jorge Luis; Salmerón Sánchez, Manuel; Gómez Ribelles, José Luís; Monleón Pradas, Manuel (Wiley, 2011)

New biodegradable block copolymer networks were synthesized from methacrylate-terminated poly(L-lactide) (mLA) and polycaprolactone (mCL) macromers. This allowed the realization of a series of materials in which the macromer ...
Biodegradable polyester networks including hydrophilic groups favor BMSCs differentiation and can be eroded by macrophage action

Fernández, Juan Manuel; Gisela Oberti, Tamara; Vikingsson, Line; Gómez Ribelles, José Luís; Cortizo, Ana (Elsevier, 2016-08)

[EN] The aim of this study is to show that introducing a small fraction of hydrophilic groups into a hydrophobic polyester favor the macrophage activity by accelerating the degradation action in aqueous media. It is also ...