[EN] Many anticancer agents used in clinics induce premature senescence in healthy tissues generating accelerated aging processes and adverse side-effects in patients. Cardiotoxicity is a well-known limiting factor of ...
Vivo Llorca, Gema(Universitat Politècnica de València, 2017-10-25)
The aim of this project is to optimize a novel nanodispositive based on silica mesoporous nanoparticles (MSNs) for genome editing in human cell lines, using CRISPR/Cas9 technology. It focuses on the synthesis and ...
[EN] In vivo detection of cellular senescence is accomplished by using mesoporous silica nanoparticles loaded with the NIR-FDA approved Nile blue (NB) dye and capped with a galactohexasaccharide (S3). NB emission at 672 ...
[EN] Acute lung injury (ALI) is a critical inflammatory syndrome, characterized by increased diffuse inflammation and severe lung damage, which represents a clinical concern due to the high morbidity and mortality in ...