Short-Time Estimation of Fractionation in Atrial Fibrillation with Coarse-Grained Correlation Dimension for Mapping the Atrial Substrate

dc.contributor.affiliationDepartamento de Ingeniería Electrónica
dc.contributor.affiliationEscuela Politécnica Superior de Gandia
dc.contributor.affiliationBiosignals & Minimally Invasive Technologies-BioMIT
dc.contributor.authorVraka, Aikaterinies_ES
dc.contributor.authorHornero, Fernandoes_ES
dc.contributor.authorBertomeu-Gonzalez, Vicentees_ES
dc.contributor.authorOsca, Joaquines_ES
dc.contributor.authorAlcaraz, Raules_ES
dc.contributor.authorRieta, J J
dc.contributor.funderGeneralitat Valencianaes_ES
dc.contributor.funderAgencia Estatal de Investigaciónes_ES
dc.contributor.funderConsejería de Educación, Cultura y Deportes, Junta de Comunidades de Castilla-La Manchaes_ES
dc.date.accessioned2020-12-17T04:32:30Z
dc.date.available2020-12-17T04:32:30Z
dc.date.issued2020-02-19es_ES
dc.description.abstract[EN] Atrial ¿brillation (AF) is currently the most common cardiac arrhythmia, with catheter ablation (CA) of the pulmonary veins (PV) being its ¿rst line therapy. Ablation of complex fractionated atrial electrograms (CFAEs) outside the PVs has demonstrated improved long-term results, but their identi¿cation requires a reliable electrogram (EGM) fractionation estimator. This study proposes a technique aimed to assist CA procedures under real-time settings. The method has been tested on three groups of recordings: Group 1 consisted of 24 highly representative EGMs, eight of each belonging to a different AF Type. Group 2 contained the entire dataset of 119 EGMs, whereas Group 3 contained 20 pseudo-real EGMs of the special Type IV AF. Coarse-grained correlation dimension (CGCD) was computed at epochs of 1 s duration, obtaining a classi¿cation accuracy of 100% in Group 1 and 84.0¿85.7% in Group 2, using 10-fold cross-validation. The receiver operating characteristics (ROC) analysis for highly fractionated EGMs, showed 100% speci¿city and sensitivity in Group 1 and 87.5% speci¿city and 93.6% sensitivity in Group 2. In addition, 100% of the pseudo-real EGMs were correctly identi¿ed as Type IV AF. This method can consistently express the fractionation level of AF EGMs and provides better performance than previous works. Its ability to compute fractionation in short-time can agilely detect sudden changes of AF Types and could be used for mapping the atrial substrate, thus assisting CA procedures under real-time settings for atrial substrate modi¿cation.en_EN
dc.description.accrualMethodSes_ES
dc.description.bibliographicCitationVraka, A.; Hornero, F.; Bertomeu-Gonzalez, V.; Osca, J.; Alcaraz, R.; Rieta, JJ. (2020). Short-Time Estimation of Fractionation in Atrial Fibrillation with Coarse-Grained Correlation Dimension for Mapping the Atrial Substrate. Entropy. 22(2):1-20. https://doi.org/10.3390/e22020232es_ES
dc.description.issue2es_ES
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dc.description.sponsorshipThis research has been supported by grants DPI2017-83952-C3 from MINECO/AEI/FEDER EU, SBPLY/17/180501/000411 from JCCM and AICO/2019/036 from GVA.es_ES
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dc.identifier.doi10.3390/e22020232es_ES
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dc.identifier.urihttps://riunet.upv.es/handle/10251/157275
dc.languageIngléses_ES
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dc.relation.publisherversionhttps://doi.org/10.3390/e22020232es_ES
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dc.rightsReconocimiento (by)es_ES
dc.rights.accessRightsAbiertoes_ES
dc.subjectAtrial fibrillationes_ES
dc.subjectCatheter ablationes_ES
dc.subjectSignal processinges_ES
dc.subjectChaos theoryes_ES
dc.subjectCoarse-grained correlation dimensiones_ES
dc.subjectComplex fractionated atrial electrogramses_ES
dc.subjectNonlinear analysises_ES
dc.subject.classificationTECNOLOGIA ELECTRONICAes_ES
dc.titleShort-Time Estimation of Fractionation in Atrial Fibrillation with Coarse-Grained Correlation Dimension for Mapping the Atrial Substratees_ES
dc.typeArtículoes_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersiones_ES
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