The Reductive Addition Oxidative Elimination Mechanism

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dc.contributor.affiliationInstituto Universitario Mixto de Tecnología Química
dc.contributor.authorLerma-Berlanga, Belén
dc.contributor.authorLeyva Perez, Antonio
dc.contributor.funderAgencia Estatal de Investigaciónes_ES
dc.date.accessioned2026-05-26T12:35:30Z
dc.date.available2026-05-26T12:35:30Z
dc.date.issued2025-03-10es_ES
dc.description.abstract[EN] The oxidative addition¿reductive elimination (OARE) mechanism of reactive molecules on metal atoms is a cornerstone of modern chemistry. However, the complementary reductive addition¿oxidative elimination (RAOE) mechanism is barely considered, despite a first reduction reaction between metal atoms and the incoming organic reactant makes chemical sense in a plethora of processes. Here we show, in a chronological order, early precedents in the literature which indicated the possibility of a general RAOE mechanism, the few systems explicitly reported so far (including a catalytic system) and some other reactions where a RAOE mechanism would satisfactorily explain the mechanistic evidences found. These examples, together, strongly suggest that researchers should consider the RAOE mechanism during their investigations, and not simply adjust their conclusions to the omnipresent OARE mechanism. This new line of thinking might open new avenues in the design of chemical reactions, particularly catalytic ones.es_ES
dc.description.accrualMethodSes_ES
dc.description.bibliographicCitationLerma-Berlanga, Belén; Leyva Perez, Antonio (2025). The Reductive Addition Oxidative Elimination Mechanism. ChemistryEurope. 3(2). https://doi.org/10.1002/ceur.202400086es_ES
dc.description.issue2es_ES
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dc.description.sponsorshipWe thank the Ministerio de Ciencia e Innovación Spain (MICIIN), for grant numbers PID2023-148441NB I00 and Severo Ochoa program CEX2021-001230-S. B. L.-B. thanks Juan de la Cierva grant (JDC2022 048323 I).es_ES
dc.description.volume3es_ES
dc.identifier.doi10.1002/ceur.202400086es_ES
dc.identifier.eissn2751-4765es_ES
dc.identifier.urihttps://riunet.upv.es/handle/10251/235428
dc.languageIngléses_ES
dc.publisherWiley-VCHes_ES
dc.relation.ispartofChemistryEuropees_ES
dc.relation.pasarelaS\584469es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2023-148441NB-I00/ES/NANORREACTORES SOLIDOS MODULABLES A ESCALA DE SUB-ANGSTROMS PARA REACCIONES ORGANICAS REGIO-IRREGULARES/es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/AEI//CEX2021-001230-S/es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/AEI//JDC2022-048323-I/es_ES
dc.relation.publisherversionhttps://doi.org/10.1002/ceur.202400086es_ES
dc.rightsReconocimiento (by)es_ES
dc.rights.accessRightsAbiertoes_ES
dc.subjectOxidative addition-reductive eliminationes_ES
dc.subjectReductive addition-oxidative eliminationes_ES
dc.subjectOrganometallic chemistryes_ES
dc.subjectCatalytic processeses_ES
dc.subjectMetal-mediated reactionses_ES
dc.subjectReaction mechanismses_ES
dc.titleThe Reductive Addition Oxidative Elimination Mechanismes_ES
dc.typeArtículoes_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersiones_ES
dspace.entity.typePublication
person.identifier735346
person.identifier250316
person.identifier.orcid0000-0003-3686-8576
person.identifier.orcid0000-0003-1063-5811
relation.isAuthorOfPublication8b444811-cc26-483b-95c2-9dc5ad94c654
relation.isAuthorOfPublication710dfb4f-4429-4ad0-9a2c-10a4c568f6c0
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