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dc.contributor.author | Lahuerta-Zamora, Luis | es_ES |
dc.contributor.author | Mellado Romero, Ana María | es_ES |
dc.date.accessioned | 2018-04-13T04:13:10Z | |
dc.date.available | 2018-04-13T04:13:10Z | |
dc.date.issued | 2017 | es_ES |
dc.identifier.issn | 1618-2642 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10251/100326 | |
dc.description.abstract | [EN] A new system for continuous flow chemiluminescence detection, based on the use of a simple and low-priced lens-free digital camera (with complementary metal oxide semiconductor technology) as a detector, is proposed for the quantitative determination of paracetamol in commercial pharmaceutical formulations. Through the camera software, AVI video files of the chemiluminescence emission are captured and then, using friendly ImageJ public domain software (from National Institutes for Health), properly processed in order to extract the analytical information. The calibration graph was found to be linear over the range 0.01¿ 0.10 mg L¿1 and over the range 1.0¿100.0 mg L¿1 of paracetamol, the limit of detection being 10 ¿g L¿1. No significative interferences were found. Paracetamol was determined in three different pharmaceutical formulations: Termalgin®, Efferalgan® and Gelocatil®. The obtained results compared well with those declared on the formulation label and with those obtained through the official analytical method of British Pharmacopoeia. | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | Springer-Verlag | es_ES |
dc.relation.ispartof | Analytical and Bioanalytical Chemistry | es_ES |
dc.rights | Reserva de todos los derechos | es_ES |
dc.subject | Flow chemiluminescence | es_ES |
dc.subject | CMOS camera | es_ES |
dc.subject | ImageJ | es_ES |
dc.subject | Pharmaceutical analysis | es_ES |
dc.subject.classification | INGENIERIA DE LA CONSTRUCCION | es_ES |
dc.title | Video approach to chemiluminescence detection using a low-cost complementary metal oxide semiconductor (CMOS)-based camera: determination of paracetamol in pharmaceutical formulations | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.1007/s00216-017-0334-6 | es_ES |
dc.rights.accessRights | Abierto | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Departamento de Ingeniería de la Construcción y de Proyectos de Ingeniería Civil - Departament d'Enginyeria de la Construcció i de Projectes d'Enginyeria Civil | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | https://doi.org/10.1007/s00216-017-0334-6 | es_ES |
dc.description.upvformatpinicio | 3891 | es_ES |
dc.description.upvformatpfin | 3898 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 409 | es_ES |
dc.description.issue | 15 | es_ES |
dc.relation.pasarela | S\348531 | es_ES |
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