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Coating typologies and constrained swelling of hyaluronic acid gels within scaffold pores

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Coating typologies and constrained swelling of hyaluronic acid gels within scaffold pores

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dc.contributor.author Arnal Pastor, María Pilar es_ES
dc.contributor.author Vallés Lluch, Ana es_ES
dc.contributor.author Keicher, Matthias es_ES
dc.contributor.author Monleón Pradas, Manuel es_ES
dc.date.accessioned 2018-04-21T04:23:06Z
dc.date.available 2018-04-21T04:23:06Z
dc.date.issued 2011 es_ES
dc.identifier.issn 0021-9797 es_ES
dc.identifier.uri http://hdl.handle.net/10251/100811
dc.description.abstract [EN] A set of elastomeric scaffolds with a well defined porous structure was prepared with a template leaching procedure and coated with hyaluronic acid solutions. Depending on the coating process parameters the hyaluronic acid deposited on the pores had configurations ranging from thin disconnected aggregates to a thick continuous layer on the pore surface. The development of the coating layer was studied by scanning electron microscopy and the materials were subjected to dynamical and equilibrium swelling experiments in a water vapor ambient of fixed activity. The porosity change due to coating and to swelling of the coating layer were determined. The hyaluronic acid coating the pores has a different swelling capacity depending on the type of layer formed, as a consequence of the scaffold constraint and of the layer typology. These factors were investigated analytically by modifying the standard theory of gel swelling. An experimental quantity is introduced which reflects the constrainment build-up on gel swelling. © 2011 Elsevier Inc. es_ES
dc.description.sponsorship The authors acknowledge the support of the FP7 NMP3-SL-2009-229239 project "Regeneration of cardiac tissue assisted by bioactive implants (RECATABI)". MMP further acknowledges the support of the Spanish Science & Innovation Ministry through project MAT2008-06434. Roberto Garcia Gomez is thanked for his help in preparing the bare scaffolds. en_EN
dc.language Inglés es_ES
dc.publisher Elsevier es_ES
dc.relation COMISION DE LAS COMUNIDADES EUROPEA/229239 es_ES
dc.relation MINISTERIO DE EDUCACION /MAT2008-06434 es_ES
dc.relation.ispartof Journal of Colloid and Interface Science es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Hyaluronic acid/hyaluronan es_ES
dc.subject Scaffold es_ES
dc.subject Swelling es_ES
dc.subject Coating layer es_ES
dc.subject Coating process parameter es_ES
dc.subject Continuous layers es_ES
dc.subject Elastomeric scaffolds es_ES
dc.subject Equilibrium swelling es_ES
dc.subject Gel swelling es_ES
dc.subject Hyaluronic acid coatings es_ES
dc.subject Hyaluronic acids es_ES
dc.subject Leaching procedures es_ES
dc.subject Pore surface es_ES
dc.subject Porosity changes es_ES
dc.subject Porous structures es_ES
dc.subject Standard theories es_ES
dc.subject Swelling capacities es_ES
dc.subject Agglomeration es_ES
dc.subject Coatings es_ES
dc.subject Gels es_ES
dc.subject Leaching es_ES
dc.subject Organic acids es_ES
dc.subject Scaffolds es_ES
dc.subject Scaffolds (biology) es_ES
dc.subject Scanning electron microscopy es_ES
dc.subject Tissue es_ES
dc.subject Water vapor es_ES
dc.subject Acrylic acid derivative es_ES
dc.subject Elastomer es_ES
dc.subject hyaluronic acid es_ES
dc.subject Molecular scaffold es_ES
dc.subject poly(ethyl acrylate) es_ES
dc.subject Unclassified drug es_ES
dc.subject Adsorption es_ES
dc.subject Article es_ES
dc.subject Chemical structure es_ES
dc.subject Controlled study es_ES
dc.subject Elasticity es_ES
dc.subject Gel es_ES
dc.subject Heart es_ES
dc.subject Humidity es_ES
dc.subject Material coating es_ES
dc.subject Porosity es_ES
dc.subject Priority journal es_ES
dc.subject Surface property es_ES
dc.subject Coated Materials, Biocompatible es_ES
dc.subject Tissue Scaffolds es_ES
dc.subject Water es_ES
dc.subject.classification TERMODINAMICA APLICADA (UPV) es_ES
dc.subject.classification MAQUINAS Y MOTORES TERMICOS es_ES
dc.title Coating typologies and constrained swelling of hyaluronic acid gels within scaffold pores es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1016/j.jcis.2011.05.013 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/229239/EU en_EN
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada es_ES
dc.description.bibliographicCitation Arnal Pastor, MP.; Vallés Lluch, A.; Keicher, M.; Monleón Pradas, M. (2011). Coating typologies and constrained swelling of hyaluronic acid gels within scaffold pores. Journal of Colloid and Interface Science. 361(1):361-369. doi:10.1016/j.jcis.2011.05.013 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1016/j.jcis.2011.05.013 es_ES
dc.description.upvformatpinicio 361 es_ES
dc.description.upvformatpfin 369 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 361 es_ES
dc.description.issue 1 es_ES
dc.relation.pasarela 211781 es_ES
dc.contributor.funder MINISTERIO DE EDUCACION es_ES
dc.contributor.funder COMISION DE LAS COMUNIDADES EUROPEA es_ES


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