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The effects of low levels of aflatoxin B1 on health, growth performance and reproductivity in male rabbits

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The effects of low levels of aflatoxin B1 on health, growth performance and reproductivity in male rabbits

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dc.contributor.author Sun, Yawang es_ES
dc.contributor.author Dong, Guozhong es_ES
dc.contributor.author E, Guangxin es_ES
dc.contributor.author Liao, Min es_ES
dc.contributor.author Tao, Lin es_ES
dc.contributor.author Lv, Jingzhi es_ES
dc.date.accessioned 2018-06-29T10:22:40Z
dc.date.available 2018-06-29T10:22:40Z
dc.date.issued 2018-06-28
dc.identifier.issn 1257-5011
dc.identifier.uri http://hdl.handle.net/10251/104847
dc.description.abstract [EN] This study investigated the chronic effects of relatively low exposure to aflatoxin B1 (AFB1) on the growth performance, immune situation and reproduction in male rabbits. Bucks (n=32, 4.82±0.22 kg) were individually assigned to 4 treatments (8 replicates each) using a randomised complete block design. Four diets containing 0, 0.02, 0.05, and 0.1 mg AFB1/kg, were provided to bucks for 8 wk. Growth performance and semen quality were measured. Blood, organ and tissue samples were collected to measure haematological indices, liver function, organ weights and immune parameters. Compared to control, AFB1-contaminated diets reduced body weight and average daily gain (P<0.05), altered certain haematological indices and liver function with decreased monocytes percentage and mean corpuscular haemoglobin concentration, and increased plateletcrit and albumin (P<0.05), slightly impaired reproductive parameters with enhanced ratio of morphologically abnormal sperm cells at early stage and reduced post-stage acrosome integrity, testis weight and serum testosterone concentration (P<0.05), decreased immune function with reduced relative liver weight (%) and tumour necrosis factor-α levels in serum and liver tissue, and increased serum 8-hydroxy-2’-deoxyguanosine levels (P<0.05). Furthermore, bucks fed diets with relatively high AFB1 (0.05 and 0.1 mg AFB1/kg) had reduced red blood cell and haematocrit (P<0.05) in contrast with the low AFB1 group (0.02 mg AFB1/kg). In conclusion, diets containing 0.05 and 0.1 mg AFB1/kg had negative effects on bucks’ growth performance, haematology, reproductivity and immune function, whereas diet containing 0.02 mg AFB1/kg had only minor effects on the parameters measured. es_ES
dc.description.sponsorship The study was funded by the Fundamental Research Funds for the Central Universities (XDJK2015C081). es_ES
dc.language Inglés es_ES
dc.publisher Universitat Politècnica de València
dc.relation.ispartof World Rabbit Science
dc.rights Reserva de todos los derechos es_ES
dc.subject Rabbits es_ES
dc.subject Aflatoxin es_ES
dc.subject Growth performance es_ES
dc.subject Immune function es_ES
dc.subject Reproductivity es_ES
dc.title The effects of low levels of aflatoxin B1 on health, growth performance and reproductivity in male rabbits es_ES
dc.type Artículo es_ES
dc.date.updated 2018-06-29T09:57:40Z
dc.identifier.doi 10.4995/wrs.2018.7433
dc.relation.projectID info:eu-repo/grantAgreement/Fundamental Research Funds for the Central Universities//XDJK2015C081/
dc.rights.accessRights Abierto es_ES
dc.description.bibliographicCitation Sun, Y.; Dong, G.; E, G.; Liao, M.; Tao, L.; Lv, J. (2018). The effects of low levels of aflatoxin B1 on health, growth performance and reproductivity in male rabbits. World Rabbit Science. 26(2):123-133. https://doi.org/10.4995/wrs.2018.7433 es_ES
dc.description.accrualMethod SWORD es_ES
dc.relation.publisherversion https://doi.org/10.4995/wrs.2018.7433 es_ES
dc.description.upvformatpinicio 123 es_ES
dc.description.upvformatpfin 133 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 26
dc.description.issue 2
dc.identifier.eissn 1989-8886
dc.contributor.funder Fundamental Research Funds for the Central Universities
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