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Beyond freeze-drying of biologics: vacuum-foam drying and spray freeze-drying

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Beyond freeze-drying of biologics: vacuum-foam drying and spray freeze-drying

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dc.contributor.author Langford, A. es_ES
dc.contributor.author Balthazor, B. es_ES
dc.contributor.author Bhatnagar, B. es_ES
dc.contributor.author Tchessalov, S. es_ES
dc.contributor.author Hageman, M.J. es_ES
dc.contributor.author Lukas, A. es_ES
dc.contributor.author Plitzko, M. es_ES
dc.contributor.author Luy, B. es_ES
dc.contributor.author Ohtake, S. es_ES
dc.date.accessioned 2019-02-27T07:47:34Z
dc.date.available 2019-02-27T07:47:34Z
dc.date.issued 2018-09-07
dc.identifier.isbn 9788490486887
dc.identifier.uri http://hdl.handle.net/10251/117401
dc.description.abstract [EN] The complexity of biotherapeutics in development continues to increase as our capability in discovery and recombinant technology improves. While safety and efficacy remain the two critical aspects of all therapeutics, ensuring adequate stability is a challenge. Freeze-drying is a commonly-used processing technique to enhance the stability of biotherapeutic products, although the lengthy process time and low energy efficiency have led to the search for, and evaluation of, next-generation drying technologies, including spray freeze-drying and vaccum-foam drying. Both processes result in dosage forms that vary considerably from those produced by lyophilization and possess physical properties that may be deemed superior for their intended applications. es_ES
dc.format.extent 8 es_ES
dc.language Inglés es_ES
dc.publisher Editorial Universitat Politècnica de València es_ES
dc.relation.ispartof IDS 2018. 21st International Drying Symposium Proceedings es_ES
dc.rights Reconocimiento - No comercial - Sin obra derivada (by-nc-nd) es_ES
dc.subject Drying es_ES
dc.subject Dehydration es_ES
dc.subject Dewatering es_ES
dc.subject Emerging technologies es_ES
dc.subject Products quality es_ES
dc.subject Process control es_ES
dc.subject Environmental es_ES
dc.subject Evaporation es_ES
dc.subject Sublimation es_ES
dc.subject Diffusion es_ES
dc.subject Energy es_ES
dc.subject Intensification es_ES
dc.subject Vacuum-foam es_ES
dc.subject Vacuum-foam drying es_ES
dc.subject Spray freeze-drying es_ES
dc.subject Lyophilization es_ES
dc.subject Biotherapeutics es_ES
dc.subject Stabilization es_ES
dc.title Beyond freeze-drying of biologics: vacuum-foam drying and spray freeze-drying es_ES
dc.type Capítulo de libro es_ES
dc.type Comunicación en congreso es_ES
dc.identifier.doi 10.4995/IDS2018.2018.7855
dc.rights.accessRights Abierto es_ES
dc.description.bibliographicCitation Langford, A.; Balthazor, B.; Bhatnagar, B.; Tchessalov, S.; Hageman, M.; Lukas, A.; Plitzko, M.... (2018). Beyond freeze-drying of biologics: vacuum-foam drying and spray freeze-drying. En IDS 2018. 21st International Drying Symposium Proceedings. Editorial Universitat Politècnica de València. 41-48. https://doi.org/10.4995/IDS2018.2018.7855 es_ES
dc.description.accrualMethod OCS es_ES
dc.relation.conferencename 21st International Drying Symposium es_ES
dc.relation.conferencedate Septiembre 11-14,2018 es_ES
dc.relation.conferenceplace Valencia, Spain es_ES
dc.relation.publisherversion http://ocs.editorial.upv.es/index.php/IDS/ids2018/paper/view/7855 es_ES
dc.description.upvformatpinicio 41 es_ES
dc.description.upvformatpfin 48 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.relation.pasarela OCS\7855 es_ES


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