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dc.contributor.author | Zambon, Alessandro | es_ES |
dc.contributor.author | Giobbe, Giovanni | es_ES |
dc.contributor.author | Vetralla, Massimo | es_ES |
dc.contributor.author | Michelino, Filippo | es_ES |
dc.contributor.author | Urbani, Luca | es_ES |
dc.contributor.author | Pantano, Maria | es_ES |
dc.contributor.author | Pugno, Nicola | es_ES |
dc.contributor.author | De Coppi, Paolo | es_ES |
dc.contributor.author | Elvassore, Nicola | es_ES |
dc.contributor.author | Spilimbergo, Sara | es_ES |
dc.date.accessioned | 2019-03-07T07:30:01Z | |
dc.date.available | 2019-03-07T07:30:01Z | |
dc.date.issued | 2018-09-07 | |
dc.identifier.isbn | 9788490486887 | |
dc.identifier.uri | http://hdl.handle.net/10251/117776 | |
dc.description.abstract | [EN] Dried and sterile acellular esophageal matrix was obtained within a new drying process based on the use of supercritical carbon dioxide (SC-CO2). Experiments were performed coupling a conventional detergent enzymatic treatment with two different drying methods: (i) SC-CO2 drying alone; (ii) dehydration in ethanol and a subsequent SC-CO2 drying. Long term preservation was achieved for several months after drying, demonstrating the maintenance of extracellular matrix (ECM) structure, mechanical properties and biocompatibility within cell repopulation studies in vitro. Overall, the results highlighted the potential of this novel technology to obtain a dry and sterile acellular matrix that can be easily stored for oesophageal regeneration in patients with emergency need. | es_ES |
dc.description.sponsorship | The research leading to these results received funding from Cassa di Risparmio di Trento e Rovereto (CaRiTRo) within the research project "Supercritical decellularization of engineered tissues for clinical application", biomedical science section, 2013. We thanks Lorenza Lazzari for the donation of BM-MSCs from the Cell Factory Bank (Milan-Italy). | es_ES |
dc.format.extent | 7 | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | Editorial Universitat Politècnica de València | es_ES |
dc.relation.ispartof | IDS 2018. 21st International Drying Symposium Proceedings | es_ES |
dc.rights | Reconocimiento - No comercial - Sin obra derivada (by-nc-nd) | es_ES |
dc.subject | Drying | es_ES |
dc.subject | Dehydration | es_ES |
dc.subject | Dewatering | es_ES |
dc.subject | Emerging technologies | es_ES |
dc.subject | Products quality | es_ES |
dc.subject | Process control | es_ES |
dc.subject | Environmental | es_ES |
dc.subject | Evaporation | es_ES |
dc.subject | Sublimation | es_ES |
dc.subject | Diffusion | es_ES |
dc.subject | Energy | es_ES |
dc.subject | Intensification | es_ES |
dc.subject | Decellularized tissue | es_ES |
dc.subject | Supercritical drying | es_ES |
dc.subject | Carbon dioxide | es_ES |
dc.subject | Tissue engineering | es_ES |
dc.subject | Long term storage | es_ES |
dc.title | Long-term maintenance of dried acellular matrices | es_ES |
dc.type | Capítulo de libro | es_ES |
dc.type | Comunicación en congreso | es_ES |
dc.identifier.doi | 10.4995/IDS2018.2018.7844 | |
dc.rights.accessRights | Abierto | es_ES |
dc.description.bibliographicCitation | Zambon, A.; Giobbe, G.; Vetralla, M.; Michelino, F.; Urbani, L.; Pantano, M.; Pugno, N.... (2018). Long-term maintenance of dried acellular matrices. En IDS 2018. 21st International Drying Symposium Proceedings. Editorial Universitat Politècnica de València. 1091-1097. https://doi.org/10.4995/IDS2018.2018.7844 | es_ES |
dc.description.accrualMethod | OCS | es_ES |
dc.relation.conferencename | 21st International Drying Symposium | es_ES |
dc.relation.conferencedate | Septiembre 11-14, 2018 | es_ES |
dc.relation.conferenceplace | Valencia, Spain | es_ES |
dc.relation.publisherversion | http://ocs.editorial.upv.es/index.php/IDS/ids2018/paper/view/7844 | es_ES |
dc.description.upvformatpinicio | 1091 | es_ES |
dc.description.upvformatpfin | 1097 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.relation.pasarela | OCS\7844 | es_ES |
dc.contributor.funder | Fondazione Cassa Di Risparmio Di Trento E Rovereto |