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Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice

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Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice

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dc.contributor.author Gutiérrez, J.P. es_ES
dc.contributor.author Nieto, B. es_ES
dc.contributor.author Piqueras, P. es_ES
dc.contributor.author Ibañez Escriche, Noelia es_ES
dc.contributor.author Salgado, C. es_ES
dc.date.accessioned 2019-07-04T20:00:38Z
dc.date.available 2019-07-04T20:00:38Z
dc.date.issued 2006 es_ES
dc.identifier.issn 0999-193X es_ES
dc.identifier.uri http://hdl.handle.net/10251/123194
dc.description.abstract [EN] The aim of this research was to explore the genetic parameters associated with environmental variability for litter size (LS), litter weight (LW) and mean individual birth weight (IW) in mice before canalisation. The analyses were conducted on an experimental mice population designed to reduce environmental variability for LS. The analysed database included 1976 records for LW and IW and 4129 records for LS. The total number of individuals included in the analysed pedigree was 3997. Heritabilities estimated for the traits under an initial exploratory approach varied from 0.099 to 0.101 for LS, from 0.112 to 0.148 for LW and from 0.028 to 0.033 for IW. The means of the posterior distribution of the heritability under a Bayesian approach were the following: 0.10 (LS), 0.13 (LW) and 0.03 (IW). In general, the heritabilities estimated under the initial exploratory approach for the environmental variability of the analysed traits were low. Genetic correlations estimated between the trait and its variability reached values of -0.929 (LS), -0.815 (LW) and 0.969 (IW). The results presented here for the first time in mice may suggest a genetic basis for variability of the evaluated traits, thus opening the possibility to be implemented in selection schemes. es_ES
dc.description.sponsorship This research was partially financed by a grant from the University Complutense of Madrid, n◦ UCM PR1/03-11650. We thank Dr. Félix Goyache for comments on the manuscript.
dc.language Inglés es_ES
dc.publisher Springer (Biomed Central Ltd.) es_ES
dc.relation UCM PR1/03-11650
dc.relation.ispartof Genetics Selection Evolution es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject Canalisation es_ES
dc.subject Variability es_ES
dc.subject Mice es_ES
dc.subject Litter size es_ES
dc.subject Litter weight es_ES
dc.subject.classification PRODUCCION ANIMAL es_ES
dc.title Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1051/gse:2006014 es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ciencia Animal - Departament de Ciència Animal es_ES
dc.description.bibliographicCitation Gutiérrez, J.; Nieto, B.; Piqueras, P.; Ibañez Escriche, N.; Salgado, C. (2006). Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice. Genetics Selection Evolution. 38(5):445-462. https://doi.org/10.1051/gse:2006014 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://doi.org/10.1051/gse:2006014 es_ES
dc.description.upvformatpinicio 445 es_ES
dc.description.upvformatpfin 462 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 38 es_ES
dc.description.issue 5 es_ES
dc.identifier.pmid 16954039
dc.identifier.pmcid PMC2689256
dc.relation.pasarela S\387678 es_ES
dc.contributor.funder Universidad Complutense de Madrid


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