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Regio- and Stereoselective Synthesis of 3-Pyrazolylidene-2-oxindole Compounds by Nucleophilic Vinylic Substitution of (E)-3-(Nitromethylene)indolin-2-one

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Regio- and Stereoselective Synthesis of 3-Pyrazolylidene-2-oxindole Compounds by Nucleophilic Vinylic Substitution of (E)-3-(Nitromethylene)indolin-2-one

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Vila, C.; Slack, S.; Blay, G.; Muñoz Roca, MDC.; Pedro, JR. (2019). Regio- and Stereoselective Synthesis of 3-Pyrazolylidene-2-oxindole Compounds by Nucleophilic Vinylic Substitution of (E)-3-(Nitromethylene)indolin-2-one. Advanced Synthesis & Catalysis. 361(8):1902-1907. https://doi.org/10.1002/adsc.201900048

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Título: Regio- and Stereoselective Synthesis of 3-Pyrazolylidene-2-oxindole Compounds by Nucleophilic Vinylic Substitution of (E)-3-(Nitromethylene)indolin-2-one
Autor: Vila, C. Slack, S. Blay, G. Muñoz Roca, María Del Carmen Pedro, J. R.
Entidad UPV: Universitat Politècnica de València. Departamento de Física Aplicada - Departament de Física Aplicada
Fecha difusión:
Resumen:
[EN] A highly regio- and stereoselective synthesis of 3-alkylidene-2-oxindoles has been described through a nucleophilic vinylic substitution (SNV) of (E)-3-(nitromethylene)indolin-2-one using pyrazol-3-ones as nucleophiles ...[+]
Palabras clave: Regioselectivity , Pyrazolone , 2-oxindole , Stereoselectivity , Vinylic substitution
Derechos de uso: Reserva de todos los derechos
Fuente:
Advanced Synthesis & Catalysis. (issn: 1615-4150 )
DOI: 10.1002/adsc.201900048
Editorial:
John Wiley & Sons
Versión del editor: https://doi.org/10.1002/adsc.201900048
Código del Proyecto:
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2017-84900-P/ES/REACCIONES DE ADICION ENANTIOSELECTIVAS MEDIANTE SISTEMAS MULTICATALITICOS. HERRAMIENTAS PARA LA SINTESIS EFICIENTE DE MOLECULAS CON ACTIVIDAD FARMACOLOGICA/
info:eu-repo/grantAgreement/MINECO//RYC-2016-20187/
Agradecimientos:
Financial support from the Agencia Estatal de Investigacion (AEI, Spanish Government) and Fondo Europeo de Desarrollo Regional (FEDER, European Union) (CTQ2017-84900-P) is acknowledged. C.V. thanks the Spanish Government ...[+]
Tipo: Artículo

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CCDC 1889981 (3 ka) contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data_request/cif.

CCDC 1890014 (5 aa) contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data_request/cif.

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