Moreno, A.; Salgado, C.; Piqueras, P.; Gutiérrez, JP.; Toro Ibáñez, MA.; Ibáñez-Escriche, N.; Nieto, B. (2011). Restricting inbreeding while maintaining selection response for weight gain in Mus musculus. Journal of Animal Breeding and Genetics. 128(4):276-283. https://doi.org/10.1111/j.1439-0388.2011.00933.x
Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/138735
Title:
|
Restricting inbreeding while maintaining selection response for weight gain in Mus musculus
|
Author:
|
Moreno, A.
Salgado, C.
Piqueras, P.
Gutiérrez, J. P.
Toro Ibáñez, M. A.
Ibáñez-Escriche, Noelia
Nieto, B.
|
UPV Unit:
|
Universitat Politècnica de València. Departamento de Ciencia Animal - Departament de Ciència Animal
|
Issued date:
|
|
Abstract:
|
[EN] An experiment with mice was designed to test the relative efficiency of three selection methods that help to minimize the rate of inbreeding during selection. A common house mice (Mus musculus) population was selected ...[+]
[EN] An experiment with mice was designed to test the relative efficiency of three selection methods that help to minimize the rate of inbreeding during selection. A common house mice (Mus musculus) population was selected for 17 generations to increase the weight gain between 21 and 42 days. The population was split at random into three lines A, B and C where three selection methods were applied: individual selection and random mating, weighted selection with random mating and individual selection with minimum coancestry mating, respectively. There were three replicates for each line. Cumulated selection response was similar in the three lines, but there were differences in the level of inbreeding attained (in percentage): 31.24 (method A), 24.72 (method B) and 27.88 (method C). As consequence, lines B and C (weighted selection and minimum coancestry) showed a lower value of deterioration of fitness traits (the intrauterine mortality and the mortality at birth) than line A (random mating).
[-]
|
Subjects:
|
Inbreeding
,
Mice
,
Minimum coancestry
,
Selection
,
Weight gain
,
Weighted selection
|
Copyrigths:
|
Cerrado |
Source:
|
Journal of Animal Breeding and Genetics. (issn:
0931-2668
)
|
DOI:
|
10.1111/j.1439-0388.2011.00933.x
|
Publisher:
|
Blackwell Publishing
|
Publisher version:
|
https://doi.org/10.1111/j.1439-0388.2011.00933.x
|
Project ID:
|
MEC/AGL2008-00794
|
Thanks:
|
This paper was partially funded by a grant from the Spanish Government (AGL2008-00794).
|
Type:
|
Artículo
|