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New structural insights into the role of TROVE2 complexes in the on-set and pathogenesis of systemic lupus eythematosus determined by a combiantion of QCM-D and DPI

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New structural insights into the role of TROVE2 complexes in the on-set and pathogenesis of systemic lupus eythematosus determined by a combiantion of QCM-D and DPI

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Juste-Dolz, AM.; Do Nascimento, NM.; Monzó, IS.; Grau-García, E.; Roman-Ivorra, JA.; López-Paz, JL.; Escorihuela Fuentes, J.... (2019). New structural insights into the role of TROVE2 complexes in the on-set and pathogenesis of systemic lupus eythematosus determined by a combiantion of QCM-D and DPI. Analytical and Bioanalytical Chemistry. 411(19):4709-4720. https://doi.org/10.1007/s00216-018-1407-x

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Title: New structural insights into the role of TROVE2 complexes in the on-set and pathogenesis of systemic lupus eythematosus determined by a combiantion of QCM-D and DPI
Author: Juste-Dolz, Augusto Miguel Do Nascimento, Noelle Mariane Monzó, Isidro S. Grau-García, Elena Roman-Ivorra, J. A. López-Paz, José Luis Escorihuela Fuentes, Jorge Puchades, Rosa Morais, Sergi Giménez-Romero, David Maquieira Catala, Angel
UPV Unit: Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada
Universitat Politècnica de València. Departamento de Química - Departament de Química
Universitat Politècnica de València. Instituto de Reconocimiento Molecular y Desarrollo Tecnológico - Institut de Reconeixement Molecular i Desenvolupament Tecnològic
Issued date:
Abstract:
[EN] The mechanism of self-recognition of the autoantigen TROVE2, a common biomarker in autoimmune diseases, has been studied with a quartz crystal microbalance with dissipation monitoring (QCM-D) and dual polarization ...[+]
Subjects: TROVE2 , Antibody bipolar bridging , Systemic lupus erythematosus , Epitope mapping , QCM-D , Dual polarization interferometry
Copyrigths: Reserva de todos los derechos
Source:
Analytical and Bioanalytical Chemistry. (issn: 1618-2642 )
DOI: 10.1007/s00216-018-1407-x
Publisher:
Springer-Verlag
Publisher version: https://doi.org/10.1007/s00216-018-1407-x
Project ID:
MINECO/CTQ2013-42914-R
GENERALITAT VALENCIANA/PROMETEOII/2014/040
MINECO/CTQ2013-45875-R
Description: The final publication is available at link.springer.com.
Thanks:
We would like to thank Sylvia Daunert for her invaluable help with the discussion of the paper. Furthermore, we acknowledge financial support from the Generalitat Valenciana (GVA-PROMETEOII/2014/040) as well as the Spanish ...[+]
Type: Artículo

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