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A versatile drug delivery system targeting senescent cells

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A versatile drug delivery system targeting senescent cells

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Muñoz-Espín, D.; Rovira, M.; Galiana, I.; Giménez Morales, C.; Lozano-Torres, B.; Páez Ribes, M.; Llanos, S.... (2018). A versatile drug delivery system targeting senescent cells. EMBO Molecular Medicine. 10(9). https://doi.org/10.15252/emmm.201809355

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Title: A versatile drug delivery system targeting senescent cells
Author: Muñoz-Espín, Daniel Rovira, M. Galiana, Irene Giménez Morales, Cristina Lozano-Torres, Beatriz Páez Ribes, M. LLanos, Susana Chaib, Selim Muñoz-Martín, M. Ucero, Alvaro C. Garaulet, G. Mulero, F. Dann, S.G. VanArsdale, T. Shields, D.J. Bernardos Bau, Andrea Murguía, Jose R. Martínez-Máñez, Ramón
UPV Unit: Universitat Politècnica de València. Departamento de Química - Departament de Química
Universitat Politècnica de València. Departamento de Biotecnología - Departament de Biotecnologia
Issued date:
Abstract:
[EN] Senescent cells accumulate in multiple aging-associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here, we take advantage of the high lysosomal beta-galactosidase ...[+]
Subjects: Chemotherapy , Fibrosis , Nanomedicine , Palbociclib , Senescence
Copyrigths: Reconocimiento (by)
Source:
EMBO Molecular Medicine. (issn: 1757-4676 )
DOI: 10.15252/emmm.201809355
Publisher:
EMBO
Publisher version: https://doi.org/10.15252/emmm.201809355
Project ID:
info:eu-repo/grantAgreement/MINECO//RYC-2013-14471/ES/RYC-2013-14471/
...[+]
info:eu-repo/grantAgreement/MINECO//RYC-2013-14471/ES/RYC-2013-14471/
info:eu-repo/grantAgreement/MINECO//BFU2014-60020-R/ES/LA SENESCENCIA CELULAR COMO COMPONENTE ACTIVO EN LA REMODELACION DE TEJIDOS/
info:eu-repo/grantAgreement/CRUK//C9685%2FA25177/
info:eu-repo/grantAgreement/GVA//PROMETEOII%2F2014%2F047/ES/Nuevas aproximaciones para el diseño de materiales de liberación controlada y la detección de compuestos peligrosos/
info:eu-repo/grantAgreement/MINECO//MAT2015-64139-C4-1-R/ES/NANOMATERIALES INTELIGENTES, SONDAS Y DISPOSITIVOS PARA EL DESARROLLO INTEGRADO DE NUEVAS HERRAMIENTAS APLICADAS AL CAMPO BIOMEDICO/
info:eu-repo/grantAgreement/MINECO//DTS16%2F00205/ES/NANODISPOSITIVOS INTELIGENTES DIRIGIDOS A CÉLULAS SENESCENTES: NANO-SEN/
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Thanks:
We are grateful to D. Megias, L. Martinez, O. Dominguez, F. Al-Shahrour, C. Fustero, O. Graria, G. Garnez-Lapez, A. De Martino, P. Gonzalez, M. Udriste for technical support. Work in the laboratory of R.M.-M was funded by ...[+]
Type: Artículo

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