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Prospective multicenter real-world RAS mutation comparison between OncoBEAM-based liquid biopsy and tissue analysis in metastatic colorectal cancer

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Prospective multicenter real-world RAS mutation comparison between OncoBEAM-based liquid biopsy and tissue analysis in metastatic colorectal cancer

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García-Foncillas, J.; Tabernero, J.; Ëlez, E.; Aranda, E.; Benavides, M.; Camps-Herrrero, C.; Jantus-Lewintre, E.... (2018). Prospective multicenter real-world RAS mutation comparison between OncoBEAM-based liquid biopsy and tissue analysis in metastatic colorectal cancer. British Journal of Cancer. 119(12):1464-1470. https://doi.org/10.1038/s41416-018-0293-5

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Title: Prospective multicenter real-world RAS mutation comparison between OncoBEAM-based liquid biopsy and tissue analysis in metastatic colorectal cancer
Author: García-Foncillas, J. Tabernero, J. Ëlez, E. Aranda, E. Benavides, M. Camps-Herrrero, Carlos Jantus-Lewintre, Eloisa Lopez, R. Muinelo-Romay, L. Montagut, C. Antón, A. Lopez, G. Diaz-Rubio, E. Rojo, F. Vivancos, A.
UPV Unit: Universitat Politècnica de València. Departamento de Biotecnología - Departament de Biotecnologia
Issued date:
Abstract:
[EN] BACKGROUND: Liquid biopsy offers a minimally invasive alternative to tissue-based evaluation of mutational status in cancer. The goal of the present study was to evaluate the aggregate performance of OncoBEAM RAS ...[+]
Subjects: Circulating tumor DNA , Plus cetuximab treatment , Growth-Factor receptor , Anti-EGFR therapy , Clinical-Relevance , Digital PCR , Kras , Folfiri , Braf , Heterogeneity
Copyrigths: Reconocimiento (by)
Source:
British Journal of Cancer. (issn: 0007-0920 )
DOI: 10.1038/s41416-018-0293-5
Publisher:
Nature Publishing Group
Publisher version: https://doi.org/10.1038/s41416-018-0293-5
Thanks:
This work was supported by Sysmex Inostics, Inc as well as the AES Programme [Grant Numbers PI15/00934, PT17/0015/0006]. The funders had no involvement in the writing of this manuscript but did review for medical accuracy ...[+]
Type: Artículo

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