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Photobinding of Triflusal to Human Serum Albumin Investigated by Fluorescence, Proteomic Analysis, and Computational Studies

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Photobinding of Triflusal to Human Serum Albumin Investigated by Fluorescence, Proteomic Analysis, and Computational Studies

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Molins-Molina, O.; Pérez Ruiz, R.; Lence, E.; González-Bello, C.; Miranda Alonso, MÁ.; Jiménez Molero, MC. (2019). Photobinding of Triflusal to Human Serum Albumin Investigated by Fluorescence, Proteomic Analysis, and Computational Studies. Frontiers in Pharmacology. 10:1-9. https://doi.org/10.3389/fphar.2019.01028

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/156835

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Title: Photobinding of Triflusal to Human Serum Albumin Investigated by Fluorescence, Proteomic Analysis, and Computational Studies
Author: Molins-Molina, Oscar Pérez Ruiz, Raúl Lence, Emilio González-Bello, Concepción Miranda Alonso, Miguel Ángel Jiménez Molero, María Consuelo
UPV Unit: Universitat Politècnica de València. Departamento de Química - Departament de Química
Issued date:
Abstract:
[EN] Triflusal is a platelet antiaggregant employed for the treatment and prevention of thromboembolic diseases. After administration, it is biotransformed into its active metabolite, the 2-hydroxy-4-trifluoromethylbenzoic ...[+]
Subjects: Triflusal metabolite , Human serum albumin , Fluorescence , Proteomic analysis , Docking and molecular dynamics
Copyrigths: Reconocimiento (by)
Source:
Frontiers in Pharmacology. (eissn: 1663-9812 )
DOI: 10.3389/fphar.2019.01028
Publisher:
Frontiers Media SA
Publisher version: https://doi.org/10.3389/fphar.2019.01028
Project ID:
info:eu-repo/grantAgreement/MINECO//SAF2016-75638-R/ES/DESARROLLO DE NUEVOS FARMACOS PARA EL TRATAMIENTO DE LAS INFECCIONES BACTERIANAS MULTIRESISTENTES: APROXIMACIONES QUE INCIDEN SOBRE VIABILIDAD, RESISTENCIA Y VIRULENCIA/
...[+]
info:eu-repo/grantAgreement/MINECO//SAF2016-75638-R/ES/DESARROLLO DE NUEVOS FARMACOS PARA EL TRATAMIENTO DE LAS INFECCIONES BACTERIANAS MULTIRESISTENTES: APROXIMACIONES QUE INCIDEN SOBRE VIABILIDAD, RESISTENCIA Y VIRULENCIA/
info:eu-repo/grantAgreement/Xunta de Galicia//ED431G%2F09/
info:eu-repo/grantAgreement/ISCIII//PRB3 IPT17%2F0019/
info:eu-repo/grantAgreement/Xunta de Galicia//ED431B 2018%2F04/
info:eu-repo/grantAgreement/MINECO//BES-2014-069404/ES/BES-2014-069404/
info:eu-repo/grantAgreement/MINECO//CTQ2016-78875-P/ES/CONTROL SUPRAMOLECULAR DE LA FOTORREACTIVIDAD EN MEDIOS MICROHETEROGENOS BASADOS EN AMINOACIDOS: GELES MOLECULARES Y PROTEINAS TRANSPORTADORAS COMO NANORREACTORES/
info:eu-repo/grantAgreement/MINECO//RD16%2F0006%2F0030/ES/Asma, Reacciones Adversas y Alérgicas (ARADYAL)/
info:eu-repo/grantAgreement/GVA//PROMETEO%2F2017%2F075/ES/Reacciones fotoquímicas de biomoléculas/
info:eu-repo/grantAgreement/GVA//CIDEGENT%2F2018%2F044/
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Thanks:
We gratefully acknowledge financial support from the Spanish Government (CTQ2016-78875-P, SAF2016-75638-R, BES-2014-069404, and RETICS network ARADyAL RD16/0006/0030), the Generalitat Valenciana (PROMETEO/2017/075 and ...[+]
Type: Artículo

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