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In vitro study of cheese digestion: Effect of type of cheese and intestinal conditions on macronutrients digestibility

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In vitro study of cheese digestion: Effect of type of cheese and intestinal conditions on macronutrients digestibility

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dc.contributor.author Asensio-Grau, Andrea es_ES
dc.contributor.author Peinado, I. es_ES
dc.contributor.author Heredia Gutiérrez, Ana Belén es_ES
dc.contributor.author Andrés Grau, Ana María es_ES
dc.date.accessioned 2021-01-16T04:32:29Z
dc.date.available 2021-01-16T04:32:29Z
dc.date.issued 2019-10 es_ES
dc.identifier.issn 0023-6438 es_ES
dc.identifier.uri http://hdl.handle.net/10251/159218
dc.description.abstract [EN] Exocrine Pancreatic Insufficiency (EPI) implies maldigestion, being pancreatic enzyme replacement therapy the treatment to enhance digestibility. This study aims at analysing the influence of cheese-related factors and intestinal conditions on macronutrients digestibility. Fresh-cow, fresh-goat, mild and aged cheeses were in vitro digested under different intestinal conditions of pH (6 or 7), bile concentration (1 or 10 mmol/L) and pancreatic enzymes (0-4000 LU/g fat) in order to in vitro mimic the intestinal conditions of a healthy adult and of an individual suffering of EPI. Under intestinal conditions of EN (pH 6, bile 1 mmol/L), lipids of fresh-goat and aged cheeses were more easily digested than those of fresh-cow and mild cheeses. In fact, 2000 LU/g fat of enzymatic dosage was enough to achieve a lipolysis extent of 80 and 100% in aged and fresh-goat cheeses, respectively. In contrast, proteolysis was higher in fresh-cow cheese and ripened (mild or aged) than in fresh-goat one regardless the intestinal conditions. Only in ripened-cheeses, proteolysis significantly increased at dose of enzymes does. es_ES
dc.description.sponsorship Authors of this paper, on behalf of MyCyFAPP consortium, acknowledge the European Union and the Horizon 2020 Research and Innovation Framework Programme for funding the above-mentioned project under grant agreement number 643806. The authors would like to thank the Conselleria de Educacio i Investigacio de la Generalitat Valenciana for the PhD scholarship given to Andrea Asensio Grau. es_ES
dc.language Inglés es_ES
dc.publisher Elsevier es_ES
dc.relation GENERALITAT VALENCIANA/ACIF/2017/008 es_ES
dc.relation.ispartof LWT - Food Science and Technology es_ES
dc.rights Reconocimiento - No comercial - Sin obra derivada (by-nc-nd) es_ES
dc.subject Pancreatic insufficiency es_ES
dc.subject Cheese es_ES
dc.subject Lipolysis es_ES
dc.subject Proteolysis es_ES
dc.subject Fatty acids profile es_ES
dc.subject.classification TECNOLOGIA DE ALIMENTOS es_ES
dc.title In vitro study of cheese digestion: Effect of type of cheese and intestinal conditions on macronutrients digestibility es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1016/j.lwt.2019.108278 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/643806/EU/Innovative approach for self-management and social welfare of Cystic Fibrosis patients in Europe: development, validation and implementation of a telematics tool./ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto Universitario de Ingeniería de Alimentos para el Desarrollo - Institut Universitari d'Enginyeria d'Aliments per al Desenvolupament es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Tecnología de Alimentos - Departament de Tecnologia d'Aliments es_ES
dc.description.bibliographicCitation Asensio-Grau, A.; Peinado, I.; Heredia Gutiérrez, AB.; Andrés Grau, AM. (2019). In vitro study of cheese digestion: Effect of type of cheese and intestinal conditions on macronutrients digestibility. LWT - Food Science and Technology. 113:1-7. https://doi.org/10.1016/j.lwt.2019.108278 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1016/j.lwt.2019.108278 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 7 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 113 es_ES
dc.relation.pasarela S\389892 es_ES
dc.contributor.funder Generalitat Valenciana es_ES
dc.contributor.funder European Commission es_ES


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