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Morphology, Crystallinity, and Molecular Weight of Poly(E-caprolactone)/Graphene Oxide Hybrids

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Morphology, Crystallinity, and Molecular Weight of Poly(E-caprolactone)/Graphene Oxide Hybrids

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dc.contributor.author Castilla Cortázar, María Isabel Cecilia es_ES
dc.contributor.author Vidaurre, Ana es_ES
dc.contributor.author Marí, B. es_ES
dc.contributor.author CAMPILLO FERNANDEZ, ALBERTO JOSE es_ES
dc.date.accessioned 2021-01-30T04:31:30Z
dc.date.available 2021-01-30T04:31:30Z
dc.date.issued 2019-07 es_ES
dc.identifier.uri http://hdl.handle.net/10251/160298
dc.description.abstract [EN] A study was carried out to determine the effects of graphene oxide (GO) filler on the properties of poly(epsilon-caprolactone) (PCL) films. A series of nanocomposites were prepared, incorporating different graphene oxide filler contents (0.1, 0.2, and 0.5 wt%) by the solution mixing method, and an in-depth study was made of the morphological changes, crystallization, infrared absorbance, molecular weight, thermal properties, and biocompatibility as a function of GO content to determine their suitability for use in biomedical applications. The infrared absorbance showed the existence of intermolecular hydrogen bonds between the PCL's carbonyl groups and the GO's hydrogen-donating groups, which is in line with the apparent reduction in molecular weight at higher GO contents, indicated by the results of the gel permeation chromatography (GPC), and the thermal property analysis. Polarized optical microscopy (POM) showed that GO acts as a nucleating point for PCL crystals, increasing crystallinity and crystallization temperature. The biological properties of the composites studied indicate that adding only 0.1 wt% of GO can improve cellular viability and that the composite shows promise for use in biomedical applications. es_ES
dc.description.sponsorship This work was supported by Projects GV/2016/067 of the Generalitat Valenciana and MAT2016-76039-C4-3-R of the Spanish Ministry of Economy and Competitiveness (MINECO). The authors are grateful to M. Monleon-Pradas for his helpful comments and G. Vilarino-Feltrer for his valuable advice on the cell culture experiments. A. Vidaurre would also like to express her gratitude for the support received from CIBER-BBN, an initiative funded by the VI National R&D&i Plan 2008-2011, Iniciativa Ingenio 2010, Consolider Program, CIBER Actions financed by the Instituto de Salud Carlos III with assistance from the European Regional Development Fund. SEM, TEM and AFM were conducted by the authors at the Microscopy Service of the Universitat Politecnica de Valencia, whose advice is greatly appreciated. es_ES
dc.language Inglés es_ES
dc.publisher MDPI AG es_ES
dc.relation.ispartof Polymers es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject Hybrids es_ES
dc.subject Polycaprolactone (PCL) es_ES
dc.subject Graphene oxide (GO) es_ES
dc.subject Molecular weight es_ES
dc.subject Morphology es_ES
dc.subject FT-IR es_ES
dc.subject Biocompatibility es_ES
dc.subject.classification FISICA APLICADA es_ES
dc.subject.classification MAQUINAS Y MOTORES TERMICOS es_ES
dc.title Morphology, Crystallinity, and Molecular Weight of Poly(E-caprolactone)/Graphene Oxide Hybrids es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.3390/polym11071099 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//MAT2016-76039-C4-3-R/ES/UNA NUEVA GENERACION DE MATERIALES ELECTROACTIVOS Y BIOREACTORES PARA INGENIERIA DE TEJIDO MUSCULAR/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/GVA//GV%2F2016%2F067/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Física Aplicada - Departament de Física Aplicada es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada es_ES
dc.description.bibliographicCitation Castilla Cortázar, MIC.; Vidaurre, A.; Marí, B.; Campillo Fernandez, AJ. (2019). Morphology, Crystallinity, and Molecular Weight of Poly(E-caprolactone)/Graphene Oxide Hybrids. Polymers. 11(7):1-19. https://doi.org/10.3390/polym11071099 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.3390/polym11071099 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 19 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 11 es_ES
dc.description.issue 7 es_ES
dc.identifier.eissn 2073-4360 es_ES
dc.identifier.pmid 31261770 es_ES
dc.identifier.pmcid PMC6680561 es_ES
dc.relation.pasarela S\390594 es_ES
dc.contributor.funder Generalitat Valenciana es_ES
dc.contributor.funder Instituto de Salud Carlos III es_ES
dc.contributor.funder European Regional Development Fund es_ES
dc.contributor.funder Ministerio de Economía y Competitividad es_ES
dc.contributor.funder Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina es_ES
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