Mostrar el registro sencillo del ítem
dc.contributor.author | Martins, Paulo Magalhaes | es_ES |
dc.contributor.author | Dal Bello, Riccardo | es_ES |
dc.contributor.author | Seimetz, Michael | es_ES |
dc.contributor.author | Hermann, German | es_ES |
dc.contributor.author | Kihm, Thomas | es_ES |
dc.contributor.author | Seco, Joao | es_ES |
dc.date.accessioned | 2021-02-13T04:32:13Z | |
dc.date.available | 2021-02-13T04:32:13Z | |
dc.date.issued | 2020-05-26 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10251/161214 | |
dc.description.abstract | [EN] Tracking of single particles accelerated by synchrotrons is a subject that crosses several physics fields. The high clinical intensities used in particle therapy that can exceed 10(9)p/s make this task very challenging. The tracking of the arrival time of single particles in the ion beam is fundamental for the verification of the particle range and dose delivered to the patient. We present a prototype made of scintillating fibers which has been used to provide time-of-flight (TOF) information for three beam species currently accelerated at the Heidelberg Ion-Beam Therapy Center (HIT). We have demonstrated a time-tracker for a prompt-gamma spectroscopy system that allows for a background TOF rejection with a sub-nanosecond time resolution. | es_ES |
dc.description.sponsorship | PM was supported by a research fellowship for postdoctoral researchers from the Alexander von Humboldt Foundation, Bonn, Germany. RD was supported by the International Max Planck Research School for Quantum Dynamics in Physics, Chemistry and Biology, Heidelberg, Germany. | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | Frontiers Media | es_ES |
dc.relation.ispartof | Frontiers in Physics | es_ES |
dc.rights | Reconocimiento (by) | es_ES |
dc.subject | Prompt-gamma | es_ES |
dc.subject | Particle tracking scintillating fibers | es_ES |
dc.subject | Ion-beam therapy | es_ES |
dc.subject | Synchrotons | es_ES |
dc.title | A Single-Particle Trigger for Time-of-Flight Measurements in Prompt-Gamma Imaging | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.3389/fphy.2020.00169 | es_ES |
dc.rights.accessRights | Abierto | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Instituto de Instrumentación para Imagen Molecular - Institut d'Instrumentació per a Imatge Molecular | es_ES |
dc.description.bibliographicCitation | Martins, PM.; Dal Bello, R.; Seimetz, M.; Hermann, G.; Kihm, T.; Seco, J. (2020). A Single-Particle Trigger for Time-of-Flight Measurements in Prompt-Gamma Imaging. Frontiers in Physics. 8:1-13. https://doi.org/10.3389/fphy.2020.00169 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | https://doi.org/10.3389/fphy.2020.00169 | es_ES |
dc.description.upvformatpinicio | 1 | es_ES |
dc.description.upvformatpfin | 13 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 8 | es_ES |
dc.identifier.eissn | 2296-424X | es_ES |
dc.relation.pasarela | S\412954 | es_ES |
dc.contributor.funder | Max Planck Society | es_ES |
dc.contributor.funder | Alexander von Humboldt Foundation | es_ES |
dc.description.references | Parodi, K., Crespo, P., Eickhoff, H., Haberer, T., Pawelke, J., Schardt, D., & Enghardt, W. (2005). Random coincidences during in-beam PET measurements at microbunched therapeutic ion beams. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 545(1-2), 446-458. doi:10.1016/j.nima.2005.02.002 | es_ES |
dc.description.references | Crespo, P., Barthel, T., Frais-Kolbl, H., Griesmayer, E., Heidel, K., Parodi, K., … Enghardt, W. (2005). Suppression of random coincidences during in-beam PET measurements at ion beam radiotherapy facilities. IEEE Transactions on Nuclear Science, 52(4), 980-987. doi:10.1109/tns.2005.852637 | es_ES |
dc.description.references | Testa, E., Bajard, M., Chevallier, M., Dauvergne, D., Le Foulher, F., Freud, N., … Testa, M. (2008). Monitoring the Bragg peak location of 73MeV∕u carbon ions by means of prompt γ-ray measurements. Applied Physics Letters, 93(9), 093506. doi:10.1063/1.2975841 | es_ES |
dc.description.references | Biegun, A. K., Seravalli, E., Lopes, P. C., Rinaldi, I., Pinto, M., Oxley, D. C., … Schaart, D. R. (2012). Time-of-flight neutron rejection to improve prompt gamma imaging for proton range verification: a simulation study. Physics in Medicine and Biology, 57(20), 6429-6444. doi:10.1088/0031-9155/57/20/6429 | es_ES |
dc.description.references | Smeets, J., Roellinghoff, F., Prieels, D., Stichelbaut, F., Benilov, A., Busca, P., … Dubus, A. (2012). Prompt gamma imaging with a slit camera for real-time range control in proton therapy. Physics in Medicine and Biology, 57(11), 3371-3405. doi:10.1088/0031-9155/57/11/3371 | es_ES |
dc.description.references | Verburg, J. M., Riley, K., Bortfeld, T., & Seco, J. (2013). Energy- and time-resolved detection of prompt gamma-rays for proton range verification. Physics in Medicine and Biology, 58(20), L37-L49. doi:10.1088/0031-9155/58/20/l37 | es_ES |
dc.description.references | Golnik, C., Hueso-González, F., Müller, A., Dendooven, P., Enghardt, W., Fiedler, F., … Pausch, G. (2014). Range assessment in particle therapy based on promptγ-ray timing measurements. Physics in Medicine and Biology, 59(18), 5399-5422. doi:10.1088/0031-9155/59/18/5399 | es_ES |
dc.description.references | Cambraia Lopes, P., Clementel, E., Crespo, P., Henrotin, S., Huizenga, J., Janssens, G., … Schaart, D. R. (2015). Time-resolved imaging of prompt-gamma rays for proton range verification using a knife-edge slit camera based on digital photon counters. Physics in Medicine and Biology, 60(15), 6063-6085. doi:10.1088/0031-9155/60/15/6063 | es_ES |
dc.description.references | Petzoldt, J., Roemer, K. E., Enghardt, W., Fiedler, F., Golnik, C., Hueso-González, F., … Pausch, G. (2016). Characterization of the microbunch time structure of proton pencil beams at a clinical treatment facility. Physics in Medicine and Biology, 61(6), 2432-2456. doi:10.1088/0031-9155/61/6/2432 | es_ES |
dc.description.references | Verburg, J. M., & Seco, J. (2014). Proton range verification through prompt gamma-ray spectroscopy. Physics in Medicine and Biology, 59(23), 7089-7106. doi:10.1088/0031-9155/59/23/7089 | es_ES |
dc.description.references | Hueso-González, F., Enghardt, W., Fiedler, F., Golnik, C., Janssens, G., Petzoldt, J., … Pausch, G. (2015). First test of the prompt gamma ray timing method with heterogeneous targets at a clinical proton therapy facility. Physics in Medicine and Biology, 60(16), 6247-6272. doi:10.1088/0031-9155/60/16/6247 | es_ES |
dc.description.references | Martins, P. M., Dal Bello, R., Rinscheid, A., Roemer, K., Werner, T., Enghardt, W., … Seco, J. (2017). Prompt gamma spectroscopy for range control with CeBr3. Current Directions in Biomedical Engineering, 3(2), 113-117. doi:10.1515/cdbme-2017-0023 | es_ES |
dc.description.references | Gil, E. C., Albarrán, E. M., Minucci, E., Nüssle, G., Padolski, S., Petrov, P., … Kozhuharov, V. (2017). The beam and detector of the NA62 experiment at CERN. Journal of Instrumentation, 12(05), P05025-P05025. doi:10.1088/1748-0221/12/05/p05025 | es_ES |
dc.description.references | Schüttauf, A. (2004). Timing RPCs in FOPI. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 533(1-2), 65-68. doi:10.1016/j.nima.2004.07.002 | es_ES |
dc.description.references | Alici, A. (2012). Status and performance of the ALICE MRPC-based Time-Of-Flight detector. Journal of Instrumentation, 7(10), P10024-P10024. doi:10.1088/1748-0221/7/10/p10024 | es_ES |
dc.description.references | Blanco, A., Fonte, P., Garzon, J. A., Koenig, W., Kornakov, G., & Lopes, L. (2013). Performance of the HADES-TOF RPC wall in a Au + Au beam at 1.25 AGeV. Journal of Instrumentation, 8(01), P01004-P01004. doi:10.1088/1748-0221/8/01/p01004 | es_ES |
dc.description.references | Sadrozinski, H. F.-W., Ely, S., Fadeyev, V., Galloway, Z., Ngo, J., Parker, C., … Vinattieri, A. (2013). Ultra-fast silicon detectors. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 730, 226-231. doi:10.1016/j.nima.2013.06.033 | es_ES |
dc.description.references | Cartiglia, N., Staiano, A., Sola, V., Arcidiacono, R., Cirio, R., Cenna, F., … Zavrtanik, M. (2017). Beam test results of a 16 ps timing system based on ultra-fast silicon detectors. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 850, 83-88. doi:10.1016/j.nima.2017.01.021 | es_ES |
dc.description.references | Sadrozinski, H. F.-W., Seiden, A., & Cartiglia, N. (2017). 4D tracking with ultra-fast silicon detectors. Reports on Progress in Physics, 81(2), 026101. doi:10.1088/1361-6633/aa94d3 | es_ES |
dc.description.references | Beddar, A. S., Mackie, T. R., & Attix, F. H. (1992). Water-equivalent plastic scintillation detectors for high-energy beam dosimetry: I. Physical characteristics and theoretical considerations. Physics in Medicine and Biology, 37(10), 1883-1900. doi:10.1088/0031-9155/37/10/006 | es_ES |
dc.description.references | Beddar, A. S., Mackie, T. R., & Attix, F. H. (1992). Water-equivalent plastic scintillation detectors for high-energy beam dosimetry: II. Properties and measurements. Physics in Medicine and Biology, 37(10), 1901-1913. doi:10.1088/0031-9155/37/10/007 | es_ES |
dc.description.references | Beaulieu, L., & Beddar, S. (2016). Review of plastic and liquid scintillation dosimetry for photon, electron, and proton therapy. Physics in Medicine and Biology, 61(20), R305-R343. doi:10.1088/0031-9155/61/20/r305 | es_ES |
dc.description.references | Beddar, S., & Beaulieu, L. (Eds.). (2016). Scintillation Dosimetry. Imaging in Medical Diagnosis and Therapy. doi:10.1201/b19491 | es_ES |
dc.description.references | Marcatili, S., Collot, J., Curtoni, S., Dauvergne, D., Hostachy, J.-Y., Koumeir, C., … Yamouni, M. (2020). Ultra-fast prompt gamma detection in single proton counting regime for range monitoring in particle therapy. Physics in Medicine & Biology, 65(24), 245033. doi:10.1088/1361-6560/ab7a6c | es_ES |
dc.description.references | Kirn, T. (2017). SciFi – A large scintillating fibre tracker for LHCb. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 845, 481-485. doi:10.1016/j.nima.2016.06.057 | es_ES |
dc.description.references | Leverington, B. D., Dziewiecki, M., Renner, L., & Runze, R. (2018). A prototype scintillating fibre beam profile monitor for Ion Therapy beams. Journal of Instrumentation, 13(05), P05030-P05030. doi:10.1088/1748-0221/13/05/p05030 | es_ES |
dc.description.references | Vignati, A., Monaco, V., Attili, A., Cartiglia, N., Donetti, M., Mazinani, M. F., … Cirio, R. (2017). Innovative thin silicon detectors for monitoring of therapeutic proton beams: preliminary beam tests. Journal of Instrumentation, 12(12), C12056-C12056. doi:10.1088/1748-0221/12/12/c12056 | es_ES |
dc.description.references | Krimmer, J., Dauvergne, D., Létang, J. M., & Testa, É. (2018). Prompt-gamma monitoring in hadrontherapy: A review. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 878, 58-73. doi:10.1016/j.nima.2017.07.063 | es_ES |
dc.description.references | Pausch, G., Berthold, J., Enghardt, W., Römer, K., Straessner, A., Wagner, A., … Kögler, T. (2020). Detection systems for range monitoring in proton therapy: Needs and challenges. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 954, 161227. doi:10.1016/j.nima.2018.09.062 | es_ES |
dc.description.references | Hueso-Gonzalez, F., & Bortfeld, T. (2020). Compact Method for Proton Range Verification Based on Coaxial Prompt Gamma-Ray Monitoring: A Theoretical Study. IEEE Transactions on Radiation and Plasma Medical Sciences, 4(2), 170-183. doi:10.1109/trpms.2019.2930362 | es_ES |
dc.description.references | Haberer, T., Debus, J., Eickhoff, H., Jäkel, O., Schulz-Ertner, D., & Weber, U. (2004). The heidelberg ion therapy center. Radiotherapy and Oncology, 73, S186-S190. doi:10.1016/s0167-8140(04)80046-x | es_ES |
dc.description.references | Hara, K., Hata, K., Kim, S., Mishina, M., Sano, M., Seiya, Y., … Yasuoka, K. (1998). Radiation hardness and mechanical durability of Kuraray optical fibers. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 411(1), 31-40. doi:10.1016/s0168-9002(98)00281-2 | es_ES |
dc.description.references | Joram, C., Haefeli, G., & Leverington, B. (2015). Scintillating Fibre Tracking at High Luminosity Colliders. Journal of Instrumentation, 10(08), C08005-C08005. doi:10.1088/1748-0221/10/08/c08005 | es_ES |
dc.description.references | EkelhofRJ Studies for the LHCb SciFi Tracker - Development of Modules from Scintillating Fibres and Tests of their Radiation Hardness2016 | es_ES |
dc.description.references | Online control of particle therapy - CLaRyS collaboration1825 DauvergneD Final MediNet Network Meeting2019 | es_ES |
dc.description.references | Tessonnier, T., Mairani, A., Chen, W., Sala, P., Cerutti, F., Ferrari, A., … Parodi, K. (2018). Proton and helium ion radiotherapy for meningioma tumors: a Monte Carlo-based treatment planning comparison. Radiation Oncology, 13(1). doi:10.1186/s13014-017-0944-3 | es_ES |
dc.description.references | Mein, S., Dokic, I., Klein, C., Tessonnier, T., Böhlen, T. T., Magro, G., … Mairani, A. (2019). Biophysical modeling and experimental validation of relative biological effectiveness (RBE) for 4He ion beam therapy. Radiation Oncology, 14(1). doi:10.1186/s13014-019-1295-z | es_ES |
dc.description.references | Schoemers, C., Feldmeier, E., Naumann, J., Panse, R., Peters, A., & Haberer, T. (2015). The intensity feedback system at Heidelberg Ion-Beam Therapy Centre. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 795, 92-99. doi:10.1016/j.nima.2015.05.054 | es_ES |
dc.description.references | Werner, F., Bauer, C., Bernhard, S., Capasso, M., Diebold, S., Eisenkolb, F., … Zietara, K. (2017). Performance verification of the FlashCam prototype camera for the Cherenkov Telescope Array. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 876, 31-34. doi:10.1016/j.nima.2016.12.056 | es_ES |
dc.description.references | Actis, M., Agnetta, G., Aharonian, F., Akhperjanian, A., Aleksić, J., … Antico, F. (2011). Design concepts for the Cherenkov Telescope Array CTA: an advanced facility for ground-based high-energy gamma-ray astronomy. Experimental Astronomy, 32(3), 193-316. doi:10.1007/s10686-011-9247-0 | es_ES |
dc.description.references | Dal Bello, R., Magalhaes Martins, P., Graça, J., Hermann, G., Kihm, T., & Seco, J. (2019). Results from the experimental evaluation of CeBr scintillators for He prompt gamma spectroscopy. Medical Physics, 46(8), 3615-3626. doi:10.1002/mp.13594 | es_ES |
dc.description.references | Puehlhofer, G., Bauer, C., Bernhard, S., Capasso, M., Diebold, S., Eisenkolb, F., … Zietara, K. (2016). FlashCam: a fully-digital camera for the medium-sized telescopes of the Cherenkov Telescope Array. Proceedings of The 34th International Cosmic Ray Conference — PoS(ICRC2015). doi:10.22323/1.236.1039 | es_ES |
dc.description.references | Testa, M., Bajard, M., Chevallier, M., Dauvergne, D., Freud, N., Henriquet, P., … Testa, E. (2010). Real-time monitoring of the Bragg-peak position in ion therapy by means of single photon detection. Radiation and Environmental Biophysics, 49(3), 337-343. doi:10.1007/s00411-010-0276-2 | es_ES |
dc.description.references | Dal Bello, R., Magalhaes Martins, P., Brons, S., Hermann, G., Kihm, T., Seimetz, M., & Seco, J. (2020). Prompt gamma spectroscopy for absolute range verification of 12C ions at synchrotron-based facilities. Physics in Medicine & Biology, 65(9), 095010. doi:10.1088/1361-6560/ab7973 | es_ES |
dc.description.references | 21768 LeoWR Techniques for Nuclear and Particle Physics Experiments: A How-to Approach1994 | es_ES |
dc.description.references | Graeff, C., Weber, U., Schuy, C., Saito, N., Volz, L., Piersimoni, P., … Kraemer, M. (2018). [OA027] Helium as a range probe in carbon ion therapy. Physica Medica, 52, 11. doi:10.1016/j.ejmp.2018.06.099 | es_ES |
dc.description.references | Mazzucconi, D., Agosteo, S., Ferrarini, M., Fontana, L., Lante, V., Pullia, M., & Savazzi, S. (2018). Mixed particle beam for simultaneous treatment and online range verification in carbon ion therapy: Proof‐of‐concept study. Medical Physics, 45(11), 5234-5243. doi:10.1002/mp.13219 | es_ES |
dc.description.references | Scintillating Fiber Trackers: recent developments and applications204 BlancF 14th ICATPP Conference on Astroparticle, Particle, Space Physics and Detectors for Physics Applications2013 | es_ES |
dc.description.references | JoramC UwerU LeveringtonBD KirnT BachmannS EkelhofRJ LHCb Scintillating Fibre Tracker Engineering Design Review Report: Fibres, Mats and Modules2015 | es_ES |