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Unique functionality of 22-nt miRNAs in triggering RDR6-dependent siRNA biogenesis from target transcripts in Arabidopsis

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Unique functionality of 22-nt miRNAs in triggering RDR6-dependent siRNA biogenesis from target transcripts in Arabidopsis

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Cuperus, JT.; Carbonell, A.; Fahlgren, N.; Garcia-Ruiz, H.; Burke, RT.; Takeda, A.; Sullivan, CM.... (2010). Unique functionality of 22-nt miRNAs in triggering RDR6-dependent siRNA biogenesis from target transcripts in Arabidopsis. Nature Structural & Molecular Biology. 17(8):997-1003. https://doi.org/10.1038/nsmb.1866

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Título: Unique functionality of 22-nt miRNAs in triggering RDR6-dependent siRNA biogenesis from target transcripts in Arabidopsis
Autor: Cuperus, Josh T. CARBONELL, ALBERTO Fahlgren, Noah Garcia-Ruiz, Hernan Burke, Russell T. Takeda, Atsushi Sullivan, Christopher M. Gilbert, Sunny D. Montgomery, Taiowa A. Carrington, James C.
Entidad UPV: Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes
Fecha difusión:
Resumen:
[EN] NA interference pathways can involve amplification of secondary siRNAs by RNA-dependent RNA polymerases. In plants, RDR6-dependent secondary siRNAs arise from transcripts targeted by some microRNAs (miRNAs). Here, ...[+]
Palabras clave: MicroRNA , RNA silencing , AGO , SiRNA
Derechos de uso: Reserva de todos los derechos
Fuente:
Nature Structural & Molecular Biology. (issn: 1545-9985 )
DOI: 10.1038/nsmb.1866
Editorial:
Nature Publishing Group
Versión del editor: https://doi.org/10.1038/nsmb.1866
Código del Proyecto:
info:eu-repo/grantAgreement/NSF//0956526/US/Function of Arabidopsis Small RNA-ARGONAUTE Complexes/
info:eu-repo/grantAgreement/NSF//0618433/US/Arabidopsis 2010: Functions of Arabidopsis Small RNAs/
info:eu-repo/grantAgreement/NIH//AI043288/
info:eu-repo/grantAgreement/MICINN//BMC-2008-0188/
Agradecimientos:
A. C. was supported by a postdoctoral fellowship from the Spanish Ministerio de Ciencia e Innovacion (BMC-2008-0188). This work was supported by grants from the US National Science Foundation (MCB-0618433 and MCB-0956526), ...[+]
Tipo: Artículo

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