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Electrohysterogram for ANN-Based Prediction of Imminent Labor in Women with Threatened Preterm Labor Undergoing Tocolytic Therapy

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Electrohysterogram for ANN-Based Prediction of Imminent Labor in Women with Threatened Preterm Labor Undergoing Tocolytic Therapy

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dc.contributor.author Mas-Cabo, Javier es_ES
dc.contributor.author Prats-Boluda, Gema es_ES
dc.contributor.author Garcia-Casado, Javier es_ES
dc.contributor.author Alberola Rubio, J. es_ES
dc.contributor.author Monfort-Ortiz, R. es_ES
dc.contributor.author Martinez-Saez, C. es_ES
dc.contributor.author Perales, A. es_ES
dc.contributor.author Ye Lin, Yiyao es_ES
dc.date.accessioned 2021-03-01T08:09:11Z
dc.date.available 2021-03-01T08:09:11Z
dc.date.issued 2020-05 es_ES
dc.identifier.uri http://hdl.handle.net/10251/162582
dc.description.abstract [EN] Threatened preterm labor (TPL) is the most common cause of hospitalization in the second half of pregnancy and entails high costs for health systems. Currently, no reliable labor proximity prediction techniques are available for clinical use. Regular checks by uterine electrohysterogram (EHG) for predicting preterm labor have been widely studied. The aim of the present study was to assess the feasibility of predicting labor with a 7- and 14-day time horizon in TPL women, who may be under tocolytic treatment, using EHG and/or obstetric data. Based on 140 EHG recordings, artificial neural networks were used to develop prediction models. Non-linear EHG parameters were found to be more reliable than linear for differentiating labor in under and over 7/14 days. Using EHG and obstetric data, the <7- and <14-day labor prediction models achieved an AUC in the test group of 87.1 +/- 4.3% and 76.2 +/- 5.8%, respectively. These results suggest that EHG can be reliable for predicting imminent labor in TPL women, regardless of the tocolytic therapy stage. This paves the way for the development of diagnostic tools to help obstetricians make better decisions on treatments, hospital stays and admitting TPL women, and can therefore reduce costs and improve maternal and fetal wellbeing. es_ES
dc.description.sponsorship This work was supported by the Spanish Ministry of Economy and Competitiveness, the European Regional Development Fund (MCIU/AEI/FEDER, UE RTI2018-094449-A-I00-AR) and by the Generalitat Valenciana (AICO/2019/220). es_ES
dc.language Inglés es_ES
dc.publisher MDPI AG es_ES
dc.relation.ispartof Sensors es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject Electrohysterogram es_ES
dc.subject Uterine myoelectrical activity es_ES
dc.subject Imminent labor prediction es_ES
dc.subject Artificial network es_ES
dc.subject Tocolytic therapy es_ES
dc.subject.classification TECNOLOGIA ELECTRONICA es_ES
dc.title Electrohysterogram for ANN-Based Prediction of Imminent Labor in Women with Threatened Preterm Labor Undergoing Tocolytic Therapy es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.3390/s20092681 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-094449-A-I00/ES/ELECTROHISTEROGRAFIA PARA LA MEJORA EN LA TOMA DE DECISIONES EN SITUACIONES DE RIESGO EN OBSTETRICIA: PARTO PREMATURO E INDUCCION DEL PARTO/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/GVA//AICO%2F2019%2F220/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto Interuniversitario de Investigación en Bioingeniería y Tecnología Orientada al Ser Humano - Institut Interuniversitari d'Investigació en Bioenginyeria i Tecnologia Orientada a l'Ésser Humà es_ES
dc.contributor.affiliation Universitat Politècnica de València. Servicio de Alumnado - Servei d'Alumnat es_ES
dc.description.bibliographicCitation Mas-Cabo, J.; Prats-Boluda, G.; Garcia-Casado, J.; Alberola Rubio, J.; Monfort-Ortiz, R.; Martinez-Saez, C.; Perales, A.... (2020). Electrohysterogram for ANN-Based Prediction of Imminent Labor in Women with Threatened Preterm Labor Undergoing Tocolytic Therapy. Sensors. 20(9):1-16. https://doi.org/10.3390/s20092681 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.3390/s20092681 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 16 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 20 es_ES
dc.description.issue 9 es_ES
dc.identifier.eissn 1424-8220 es_ES
dc.identifier.pmid 32397177 es_ES
dc.identifier.pmcid PMC7248811 es_ES
dc.relation.pasarela S\414456 es_ES
dc.contributor.funder Generalitat Valenciana es_ES
dc.contributor.funder Agencia Estatal de Investigación es_ES
dc.contributor.funder European Regional Development Fund es_ES
dc.contributor.funder Ministerio de Ciencia, Innovación y Universidades es_ES
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dc.subject.ods 03.- Garantizar una vida saludable y promover el bienestar para todos y todas en todas las edades es_ES


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