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Influence of the linking bridge on the photoreactivity of benzophenone-thymine conjugates

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Influence of the linking bridge on the photoreactivity of benzophenone-thymine conjugates

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Blasco-Brusola, A.; Vayá Pérez, I.; Miranda Alonso, MÁ. (2020). Influence of the linking bridge on the photoreactivity of benzophenone-thymine conjugates. The Journal of Organic Chemistry. 85(21):14068-14076. https://doi.org/10.1021/acs.joc.0c02088

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/164825

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Title: Influence of the linking bridge on the photoreactivity of benzophenone-thymine conjugates
Author: Blasco-Brusola, Alejandro Vayá Pérez, Ignacio Miranda Alonso, Miguel Ángel
UPV Unit: Universitat Politècnica de València. Departamento de Química - Departament de Química
Issued date:
Abstract:
[EN] Benzophenone (BP) is present in a variety of bioactive molecules. This chromophore is able to photosensitize DNA damage, where one of the most relevant BP/ DNA interactions occurs with thymine (Thy). In view of the ...[+]
Subjects: Excited-State interactions , Laser flash-photolysis , DNA-Damage , 6-4 Photoproduct , Naphthalene , Repair , Ketoprofen , Drugs , Light , Photosensitization
Copyrigths: Reserva de todos los derechos
Source:
The Journal of Organic Chemistry. (issn: 0022-3263 )
DOI: 10.1021/acs.joc.0c02088
Publisher:
American Chemical Society
Publisher version: https://doi.org/10.1021/acs.joc.0c02088
Project ID:
info:eu-repo/grantAgreement/GVA//GRISOLIAP%2F2017%2F005/
info:eu-repo/grantAgreement/GVA//PROMETEO%2F2017%2F075/ES/Reacciones fotoquímicas de biomoléculas/
info:eu-repo/grantAgreement/MINECO//RYC-2015-17737/ES/RYC-2015-17737/
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2017-89416-R/ES/FUNCIONALIZACION DE NANOPARTICULAS DE ORO CON MARCADORES BIOLOGICOS Y SENSIBILIZADORES DE OXIGENO SINGLETE PARA SU USO EN BIOMEDICINA/
Thanks:
Financial support from the Spanish Government (RYC-2015-17737 and CTQ2017-89416-R) and from the Conselleria d'Educació Cultura i Esport (PROMETEO/2017/075 and GRISOLIAP/2017/005) is gratefully acknowledged. The authors ...[+]
Type: Artículo

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