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Hydrogen Abstraction from the C15 Position of the Cholesterol Skeleton

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Hydrogen Abstraction from the C15 Position of the Cholesterol Skeleton

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Palumbo, F.; Andreu Ros, MI.; Brunetti, M.; Schmallegger, M.; Gescheidt, G.; Neshchadin, D.; Miranda Alonso, MÁ. (2019). Hydrogen Abstraction from the C15 Position of the Cholesterol Skeleton. The Journal of Organic Chemistry. 84(23):15184-15191. https://doi.org/10.1021/acs.joc.9b02181

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/166456

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Title: Hydrogen Abstraction from the C15 Position of the Cholesterol Skeleton
Author: Palumbo, Fabrizio Andreu Ros, María Inmaculada Brunetti, M. Schmallegger, Max Gescheidt, Georg Neshchadin, Dmytro Miranda Alonso, Miguel Ángel
UPV Unit: Universitat Politècnica de València. Departamento de Química - Departament de Química
Universitat Politècnica de València. Instituto Universitario Mixto de Tecnología Química - Institut Universitari Mixt de Tecnologia Química
Issued date:
Abstract:
[EN] Cholesterol (Ch) is an integral part of cell membrane, where it is prone to oxidation. In humans, oxidation of Ch is commonly linked to various pathologies like Alzheimer's disease, atherosclerosis, and even cancer, ...[+]
Subjects: Cholesterol , CIDNP , Laser flash photolysis , Radicals , Steady-State Photolysis
Copyrigths: Reserva de todos los derechos
Source:
The Journal of Organic Chemistry. (issn: 0022-3263 )
DOI: 10.1021/acs.joc.9b02181
Publisher:
American Chemical Society
Publisher version: https://doi.org/10.1021/acs.joc.9b02181
Project ID:
info:eu-repo/grantAgreement/GVA//PROMETEO%2F2016%2F120/
info:eu-repo/grantAgreement/GVA//PROMETEO%2F2017%2F075/ES/Reacciones fotoquímicas de biomoléculas/
info:eu-repo/grantAgreement/MINECO//CPII16%2F00052/ES/CPII16%2F00052/
info:eu-repo/grantAgreement/MECD//AP2012-1693/ES/AP2012-1693/
info:eu-repo/grantAgreement/MINECO//PI16%2F01877/ES/Estrategia integrada de fotodiagnóstico combinando evaluación clínica, ensayos biológicos y estudios mecanísticos/
Thanks:
This work was supported by the Carlos III Institute of Health (Grants No. PII6/01877, "Miguel Servet fellowship" CPII16/00052 to I.A.), and by the Generalitat Valenciana (Prometeo 2017/075). We would like to thank Dr Fedora ...[+]
Type: Artículo

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