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Real-time monitoring of fenitrothion in water samples using a silicon nanophotonic biosensor

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Real-time monitoring of fenitrothion in water samples using a silicon nanophotonic biosensor

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dc.contributor.author Ramirez-Priego, Patricia es_ES
dc.contributor.author Estévez, M.-Carmen es_ES
dc.contributor.author Díaz-Luisravelo, Heriberto J. es_ES
dc.contributor.author Manclus Ciscar, Juan José es_ES
dc.contributor.author Montoya, Ángel es_ES
dc.contributor.author Lechuga, Laura M. es_ES
dc.date.accessioned 2021-06-10T03:31:20Z
dc.date.available 2021-06-10T03:31:20Z
dc.date.issued 2021-04-01 es_ES
dc.identifier.issn 0003-2670 es_ES
dc.identifier.uri http://hdl.handle.net/10251/167735
dc.description.abstract [EN] Due to the large quantities of pesticides extensively used and their impact on the environment and human health, a prompt and reliable sensing technique could constitute an excellent tool for in-situ monitoring. With this aim, we have applied a highly sensitive photonic biosensor based on a bimodal waveguide interferometer (BiMW) for the rapid, label-free, and speci¿c quanti¿cation of fenitrothion (FN) directly in tap water samples. After an optimization protocol, the biosensor achieved a limit of detection (LOD) of 0.29 ng mL¿¿1 (1.05 nM) and a half-maximal inhibitory concentration (IC50)of 1.71 ng mL¿¿1 (6.09 nM) using a competitive immunoassay and employing diluted tap water. Moreover, the biosensor was successfully employed to determine FN concentration in blind tap water samples obtaining excellent recovery percentages with a time-to-result of only 20 min without any sample pre-treatment. The features of the biosensor suggest its potential application for real time, fast and sensitive screening of FN in water samples as an analytical tool for the monitoring of the water quality. es_ES
dc.description.sponsorship This work received financial support from DIONISOS Project (Retos Colaboracion RTC-2017-6222-5). The ICN2 is funded by the CERCA programme/Generalitat de Catalunya. The ICN2 is supported by the Severo Ochoa Centres of Excellence programme, funded by the Spanish Research Agency (AEI, grant no. SEV-2017-0706) es_ES
dc.language Inglés es_ES
dc.publisher Elsevier es_ES
dc.relation.ispartof Analytica Chimica Acta es_ES
dc.rights Reconocimiento - No comercial - Sin obra derivada (by-nc-nd) es_ES
dc.subject Silicon photonics es_ES
dc.subject Optical sensor es_ES
dc.subject Environmental monitoring es_ES
dc.subject Pesticide es_ES
dc.subject Organophosphate es_ES
dc.subject Fenitrothion es_ES
dc.subject Label-free es_ES
dc.subject.classification TECNOLOGIA ELECTRONICA es_ES
dc.title Real-time monitoring of fenitrothion in water samples using a silicon nanophotonic biosensor es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1016/j.aca.2021.338276 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/AEI//SEV-2017-0706/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/AEI//RTC-2017-6222-5/ES/Desarrollo de inmunoreactivos y biosensores para el análisis de trazadores en yacimientos petrolíferos (DIONISIOS)/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica es_ES
dc.description.bibliographicCitation Ramirez-Priego, P.; Estévez, M.; Díaz-Luisravelo, HJ.; Manclus Ciscar, JJ.; Montoya, Á.; Lechuga, LM. (2021). Real-time monitoring of fenitrothion in water samples using a silicon nanophotonic biosensor. Analytica Chimica Acta. 1152:1-9. https://doi.org/10.1016/j.aca.2021.338276 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1016/j.aca.2021.338276 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 9 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 1152 es_ES
dc.identifier.pmid 33648644 es_ES
dc.relation.pasarela S\433956 es_ES
dc.contributor.funder Agencia Estatal de Investigación es_ES
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