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In Silico Hemodynamics and Filtering Evaluation of a Commercial Embolic Protection Device

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In Silico Hemodynamics and Filtering Evaluation of a Commercial Embolic Protection Device

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dc.contributor.author Gil Megías, Antonio es_ES
dc.contributor.author Quintero-Igeño, Pedro-Manuel es_ES
dc.contributor.author Mares, Andrea es_ES
dc.contributor.author Serra, Juan es_ES
dc.contributor.author Sánchez-Nevárez, Manuel Ignacio es_ES
dc.contributor.author Miralles, Manuel es_ES
dc.date.accessioned 2022-07-21T18:03:37Z
dc.date.available 2022-07-21T18:03:37Z
dc.date.issued 2021-09 es_ES
dc.identifier.issn 0090-6964 es_ES
dc.identifier.uri http://hdl.handle.net/10251/184630
dc.description.abstract [EN] During the last years, several kinds of Embolic Protection Devices (EPD) have been developed, with the aim of minimizing complication caused by thrombi generated during Carotid Artery Stenting (CAS). These devices are capable of capturing small particles generated during the intervention, avoiding cerebral stroke and improving the outcomes of the surgery. However, they have associated complications, like the increase on flow resistance associated by their use or the lack of knowledge on their actual filtration efficiency for thrombi of low size. Current work proposes a validated computational methodology in order to predict the hemodynamic features and filtering efficiency of a commercial EPD. It will be observed how Computational Fluid Dynamics predicts pressure drop with fair agreement with the experimental measurements. Finally, this work analyzes the filtration efficiency and the influence of the distribution of injected particles on this parameter. The capabilities of the filter for retaining particles of diameter below the pore size is, additionally, discussed. es_ES
dc.description.sponsorship This study ws funded by upv-la fe 2020 subprograma proyectos de innovacion (Grant No. DPECFD). es_ES
dc.language Inglés es_ES
dc.publisher Springer-Verlag es_ES
dc.relation info:eu-repo/grantAgreement/UPV/SUBPROGRAMA PARA EL DESARROLLO DE PROYECTOS DE INNOVACIÓN UPV/IIS LA FE/PI2020-11/ES/Prototipo de dispositivo de protección embólica: Análisis de eficacia y resistencia al flujo mediante mecánica de fluidos computacional/DPECFD
dc.relation.ispartof Annals of Biomedical Engineering es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Computational fluid dynamics es_ES
dc.subject Embolic protection device es_ES
dc.subject Discrete element method es_ES
dc.subject Filtration efficiency es_ES
dc.subject Hemodynamics es_ES
dc.subject.classification EXPRESION GRAFICA ARQUITECTONICA es_ES
dc.subject.classification MAQUINAS Y MOTORES TERMICOS es_ES
dc.subject.classification INGENIERIA AEROESPACIAL es_ES
dc.title In Silico Hemodynamics and Filtering Evaluation of a Commercial Embolic Protection Device es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1007/s10439-021-02846-4 es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Máquinas y Motores Térmicos - Departament de Màquines i Motors Tèrmics es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Expresión Gráfica Arquitectónica - Departament d'Expressió Gràfica Arquitectònica es_ES
dc.description.bibliographicCitation Gil Megías, A.; Quintero-Igeño, P.; Mares, A.; Serra, J.; Sánchez-Nevárez, MI.; Miralles, M. (2021). In Silico Hemodynamics and Filtering Evaluation of a Commercial Embolic Protection Device. Annals of Biomedical Engineering. 49(9):2659-2670. https://doi.org/10.1007/s10439-021-02846-4 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1007/s10439-021-02846-4 es_ES
dc.description.upvformatpinicio 2659 es_ES
dc.description.upvformatpfin 2670 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 49 es_ES
dc.description.issue 9 es_ES
dc.identifier.pmid 34405319 es_ES
dc.relation.pasarela S\453037 es_ES
dc.contributor.funder Universitat Politècnica de València es_ES
dc.contributor.funder Hospital Universitari i Politècnic La Fe es_ES


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