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A multi-omic study for uncovering molecular mechanisms associated with hyperammonemia-induced cerebellar function impairment in rats

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A multi-omic study for uncovering molecular mechanisms associated with hyperammonemia-induced cerebellar function impairment in rats

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Tarazona, S.; Carmona, H.; Conesa, A.; Llansola, M.; Felipo, V. (2021). A multi-omic study for uncovering molecular mechanisms associated with hyperammonemia-induced cerebellar function impairment in rats. Cell Biology and Toxicology. 37(1):129-149. https://doi.org/10.1007/s10565-020-09572-y

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Título: A multi-omic study for uncovering molecular mechanisms associated with hyperammonemia-induced cerebellar function impairment in rats
Autor: Tarazona, Sonia Carmona, Héctor Conesa, Ana Llansola, Marta Felipo, Vicente
Entidad UPV: Universitat Politècnica de València. Escola Tècnica Superior d'Enginyeria Informàtica
Fecha difusión:
Resumen:
[EN] Patients with liver cirrhosis may develop covert or minimal hepatic encephalopathy (MHE). Hyperammonemia (HA) and peripheral inflammation play synergistic roles in inducing the cognitive and motor alterations in MHE. ...[+]
Palabras clave: Hyperammonemia , Multi-omics , Cerebellum , Signaling pathways , Neurotransmission , Immune system
Derechos de uso: Reserva de todos los derechos
Fuente:
Cell Biology and Toxicology. (issn: 0742-2091 )
DOI: 10.1007/s10565-020-09572-y
Editorial:
Springer-Verlag
Versión del editor: https://doi.org/10.1007/s10565-020-09572-y
Código del Proyecto:
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2017-82917-R/ES/BASES MOLECULARES DE LAS ALTERACIONES NEUROLOGICAS (COGNITIVAS Y MOTORAS) EN HIPERAMONEMIA Y ENCEFALOPATIA HEPATICA. LMPLICACIONES TERAPEUTICAS/
info:eu-repo/grantAgreement/GVA//PROMETEOII%2F2014%2F033/
Agradecimientos:
This work was supported by the Ministerio de Ciencia e Innovación of Spain (SAF2017-82917-R) and Consellería Educación Generalitat Valenciana (PROMETEOII/2014/033), co-funded with European Regional Development Funds (ERDF).[+]
Tipo: Artículo

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