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Arrangement of Type IV Collagen on NH2 and COOH Functionalized Surfaces

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Arrangement of Type IV Collagen on NH2 and COOH Functionalized Surfaces

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Miranda Coelho, N.; González García, C.; Salmerón Sánchez, M.; Altankov, G. (2011). Arrangement of Type IV Collagen on NH2 and COOH Functionalized Surfaces. Biotechnology and Bioengineering. 108(12):3009-3018. doi:10.1002/bit.23265

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/34674

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Title: Arrangement of Type IV Collagen on NH2 and COOH Functionalized Surfaces
Author: Miranda Coelho, Nuno González García, Cristina Salmerón Sánchez, Manuel Altankov, George
UPV Unit: Universitat Politècnica de València. Departamento de Física Aplicada - Departament de Física Aplicada
Universitat Politècnica de València. Centro de Biomateriales e Ingeniería Tisular - Centre de Biomaterials i Enginyeria Tissular
Issued date:
Apart from the paradigm that cell-biomaterials interaction depends on the adsorption of soluble adhesive proteins we anticipate that upon distinct conditions also other, less soluble ECM proteins such as collagens, associate ...[+]
Subjects: AFM , Collagen type IV , Endothelial cells , SAMs , Surface-induced protein assembly , Vascular grafts , Actin cytoskeleton , Adhesive proteins , Adsorption patterns , Basement membrane , Cardiovascular implants , Cell spreading , Cellular response , ECM proteins , Focal adhesion kinase , Focal adhesions , Functionalizations , Functionalized surfaces , Human umbilical vein endothelial cells , I-V behavior , Integrins , Matrix proteins , Nano scale , New model , Positively charged , Protein conformation , Adhesion , Adsorption , Atomic force microscopy , Biological materials , Collagen , Complexation , Focusing , Grafts , Phosphorylation , Self assembled monolayers , Alpha1 integrin , Alpha2 integrin , Amine , Biomaterial , Carboxyl group , Collagen type 4 , Fluorescein isothiocyanate , Functional group , Article , Bioengineering , Blood vessel graft , Cell interaction , Cell structure , Cell surface , Endothelium cell , Enzyme phosphorylation , Human , Human cell , Immunofluorescence , Surface property , Umbilical vein endothelial cell , Wettability , Coated Materials, Biocompatible , Humans , Microscopy, Atomic Force , Protein Binding , Surface Properties
Copyrigths: Cerrado
Biotechnology and Bioengineering. (issn: 0006-3592 )
DOI: 10.1002/bit.23265
Publisher version: http://onlinelibrary.wiley.com/doi/10.1002/bit.23265/pdf
AFM was performed under the technical guidance of the Microscopy Service at the Universidad Politecnica de Valencia, whose advice is greatly appreciated. The work was supported by the Spanish Ministry of Science and ...[+]
Type: Artículo

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