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Feasibility study of an internally cooled bipolar applicator for RF coagulation of hepatic tissue: Experimental and computational study

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Feasibility study of an internally cooled bipolar applicator for RF coagulation of hepatic tissue: Experimental and computational study

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dc.contributor.author González Suárez, Ana es_ES
dc.contributor.author Trujillo Guillen, Macarena es_ES
dc.contributor.author Burdío Pinilla, Fernando es_ES
dc.contributor.author Andaluz Martínez, Ana María es_ES
dc.contributor.author Berjano Zanón, Enrique es_ES
dc.date.accessioned 2014-10-08T10:02:19Z
dc.date.available 2014-10-08T10:02:19Z
dc.date.issued 2012-12
dc.identifier.issn 0265-6736
dc.identifier.uri http://hdl.handle.net/10251/40730
dc.description.abstract Purpose: To study the capacity of an internally cooled radiofrequency (RF) bipolar applicator to create sufficiently deep thermal lesions in hepatic tissue. Materials and methods: Three complementary methodologies were employed to check the electrical and thermal behaviour of the applicator under test. The experimental studies were based on excised bovine (ex vivo study) and porcine liver (in vivo study) and the theoretical models were solved by means of the finite element method (FEM). Results: Experimental and computational results showed good agreement in terms of impedance progress and lesion depth (4 and 4.5 mm respectively for ex vivo conditions, and approximately 7 and 9 mm respectively for in vivo conditions), although the lesion widths were overestimated by the computer simulations. This could have been due to the method used to assess the thermal lesions; the experimental lesions were assessed by the white coagulation zone, whereas the tissue damage function was used to assess the computational lesions. Conclusions: The experimental results suggest that this applicator could create in vivo lesions to a depth of around 7mm. It was also observed that the thermal lesion is mainly confined to the area between both electrodes, which would allow lesion width to be controlled by selecting a specific applicator design. The comparison between the experimental and computational results suggests that the theoretical model could be usefully applied in further studies of the performance of this device. © 2012 Informa UK Ltd All rights reserved. es_ES
dc.description.sponsorship This work received financial support from the Spanish Plan Nacional de I+D+I del Ministerio de Ciencia e Innovacion TEC2011-27133-C02-(01 and 02), from Universitat Politecnica de Valencia (INNOVA11-01-5502; and PAID-06-11 Ref. 1988). A. Gonzalez-Suarez is the recipient of grant VaLi+D (ACIF/2011/194) from the Generalitat Valenciana. The proof-reading of this paper was funded by the Universitat Politecnica de Valencia, Spain. The authors alone are responsible for the content and writing of the paper. en_EN
dc.language Inglés es_ES
dc.publisher Informa Healthcare es_ES
dc.relation Ministerio de Ciencia e Innovacion [Plan Nacional de I+D+I TEC2011-27133-C02-(01) y TEC2011-27133-C02-(02)] es_ES
dc.relation Universitat Politècnica de València [INNOVA11-01-5502 y PAID-06-11 Ref. 1988] es_ES
dc.relation Generalitat Valenciana [grant VaLi+D (ACIF/2011/194)] es_ES
dc.relation.ispartof International Journal of Hyperthermia es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Experimental model es_ES
dc.subject Finite element method es_ES
dc.subject Hepatic resection es_ES
dc.subject Internally cooled bipolar electrode es_ES
dc.subject Radiofrequency ablation es_ES
dc.subject Animal experiment es_ES
dc.subject Animal tissue es_ES
dc.subject Blood clotting es_ES
dc.subject Controlled study es_ES
dc.subject Electric conductivity es_ES
dc.subject Electrode es_ES
dc.subject In vivo study es_ES
dc.subject Ex vivo study es_ES
dc.subject Experimental study es_ES
dc.subject Feasibility study es_ES
dc.subject Finite element analysis es_ES
dc.subject Impedance es_ES
dc.subject Liver es_ES
dc.subject Nonhuman es_ES
dc.subject Radiation applicator es_ES
dc.subject Radiofrequency es_ES
dc.subject Radiofrequency radiation es_ES
dc.subject Simulation es_ES
dc.subject Thermal injury es_ES
dc.subject Tissue injury es_ES
dc.subject.classification MATEMATICA APLICADA es_ES
dc.subject.classification TECNOLOGIA ELECTRONICA es_ES
dc.title Feasibility study of an internally cooled bipolar applicator for RF coagulation of hepatic tissue: Experimental and computational study es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.3109/02656736.2012.716900
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Matemática Aplicada - Departament de Matemàtica Aplicada es_ES
dc.description.bibliographicCitation González Suárez, A.; Trujillo Guillen, M.; Burdío Pinilla, F.; Andaluz Martínez, AM.; Berjano Zanón, E. (2012). Feasibility study of an internally cooled bipolar applicator for RF coagulation of hepatic tissue: Experimental and computational study. International Journal of Hyperthermia. 28(7):663-673. doi:10.3109/02656736.2012.716900 es_ES
dc.description.accrualMethod Senia es_ES
dc.relation.publisherversion http://dx.doi.org/10.3109/02656736.2012.716900 es_ES
dc.description.upvformatpinicio 663 es_ES
dc.description.upvformatpfin 673 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 28 es_ES
dc.description.issue 7 es_ES
dc.relation.senia 230190


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