Hanhan, EM.; Martínez Mañez, R.; Ros-Lis, JV. (2012). Highly effective activation of aryl chlorides for Suzuki coupling in aqueous media using a ferrocene-based Pd(II) diimine catalyst. Tetrahedron Letters. 53(19):2388-2391. https://doi.org/10.1016/j.tetlet.2012.02.102
Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/61062
Title:
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Highly effective activation of aryl chlorides for Suzuki coupling in aqueous media using a ferrocene-based Pd(II) diimine catalyst
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Author:
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Hanhan, Emre Murat
Martínez Mañez, Ramón
Ros-Lis, José Vicente
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UPV Unit:
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Universitat Politècnica de València. Departamento de Química - Departament de Química
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Issued date:
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Abstract:
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The Suzuki coupling of aryl chlorides with boronic acids using a ferrocene-containing Pd(II)-diimine complex as catalyst, in aqueous media, under microwave heating is reported. A small amount of the catalyst (0.1%) was ...[+]
The Suzuki coupling of aryl chlorides with boronic acids using a ferrocene-containing Pd(II)-diimine complex as catalyst, in aqueous media, under microwave heating is reported. A small amount of the catalyst (0.1%) was found to be highly effective for coupling unactivated aryl chlorides with boronic acids to form sterically hindered ortho-substituted biaryls. The same catalyst also enabled the coupling of aryl bromides and iodides with various boronic acids in very high yields. The catalyst is air stable and the catalytic reaction can be completed in 15 min. © 2012 Elsevier Ltd. All rights reserved.
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Subjects:
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Aryl chlorides
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Green chemistry
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Microwave irradiation
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Pd(II) complexes
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Suzuki coupling
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Boronic acid derivative
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Ferrocene derivative
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Imine
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Palladium complex
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Polycyclic aromatic hydrocarbon derivative
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Aqueous solution
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Article
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Catalysis
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Catalyst
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Chemical structure
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Reaction time
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Stereospecificity
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Structure analysis
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Suzuki reaction
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Copyrigths:
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Cerrado |
Source:
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Tetrahedron Letters. (issn:
0040-4039
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DOI:
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10.1016/j.tetlet.2012.02.102
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Publisher:
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Elsevier
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Publisher version:
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http://dx.doi.org/10.1016/j.tetlet.2012.02.102
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Project ID:
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info:eu-repo/grantAgreement/ZBEU//BAP-2010-13-02-02/
info:eu-repo/grantAgreement/ZBEU//BAP-2011-10-03-012/
info:eu-repo/grantAgreement/ZBEU//BAP-2011-10-03-11/
info:eu-repo/grantAgreement/MICINN//MAT2009-14564-C04-01/ES/Nanomateriales Hibridos Para El Desarrollo De "Puertas Moleculares" De Aplicacion En Procesos De Reconocimiento Y Terapeutica Y Para La Deteccion De Explosivos/
info:eu-repo/grantAgreement/GVA//PROMETEO%2F2009%2F016/ES/Ayuda prometeo 2009 para el grupo de diseño y desarrollo de sensores/
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Thanks:
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The authors thank the Research Board of Zonguldak Karaelmas University (BAP-2010-13-02-02, BAP-2011-10-03-11 and BAP-2011-10-03-012), the Spanish Government (projects MAT2009-14564-C01) and the Generalitat Valenciana ...[+]
The authors thank the Research Board of Zonguldak Karaelmas University (BAP-2010-13-02-02, BAP-2011-10-03-11 and BAP-2011-10-03-012), the Spanish Government (projects MAT2009-14564-C01) and the Generalitat Valenciana (project PROMETEO/2009/016) for support.
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Type:
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Artículo
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