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Comparison of immune response to lipopolysaccharide of rabbit does selected for litter size at weaning or founded for reproductive longevity

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Comparison of immune response to lipopolysaccharide of rabbit does selected for litter size at weaning or founded for reproductive longevity

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dc.contributor.author Ferrian, Selena es_ES
dc.contributor.author Blas Ferrer, Enrique es_ES
dc.contributor.author Larsen, T. es_ES
dc.contributor.author Sánchez Serrano, Juan Pablo es_ES
dc.contributor.author Friggens, Nicholas Charles es_ES
dc.contributor.author Corpa, J. M. es_ES
dc.contributor.author Baselga Izquierdo, Manuel es_ES
dc.contributor.author Pascual Amorós, Juan José es_ES
dc.date.accessioned 2016-03-08T11:33:03Z
dc.date.available 2016-03-08T11:33:03Z
dc.date.issued 2013-06
dc.identifier.issn 0034-5288
dc.identifier.uri http://hdl.handle.net/10251/61549
dc.description.abstract To evaluate differences in maternal lines to the immune response of reproductive rabbit does, a total of 64 animals of two different lines: (1) founded for hyper-longevity and litter size criteria (LP) and (2) selected for litter size at weaning (V) were used. Females were subjected to three different reproductive efforts: post-partum (PP) mating at first lactation and 9 kits during the second; post-weaning (PW) mating at first lactation and 9 kits during the second; and PW mating at first lactation and 5 kits during the second. At second weaning (30 days PP), an acute response was induced by intravenous infusion of lipopolysaccharide (LPS). LP females seemed to be lower affected during the hyper-acute phase than V females, showing lower plasma glucose content at 1.5 h post infusion (pi) and rectal temperature at 6 h pi; and showed higher ulterior immune response, with higher levels of C-reactive protein at 48 h pi and haptoglobin in plasma from 24 h pi. Survival test conferred a higher risk of culling for V than for LP females during the first hours after challenge. These results may suggest that, regarding immune response to LPS challenge, foundation by hyper-longevity productive criteria lead to obtain a more robust population of rabbit does, characterized by improved response ability. (C) 2013 Elsevier Ltd. All rights reserved. es_ES
dc.description.sponsorship This study has been supported by the Interministerial Commission for Science and Technology (CICYT) from the Spanish Government. Grants Number: AGL2011-30170-C02-01; AGL2011-30170-C02-02), is gratefully acknowledged. en_EN
dc.language Inglés es_ES
dc.publisher Elsevier es_ES
dc.relation Interministerial Commission for Science and Technology (CICYT) from the Spanish Government [AGL2011-30170-C02-01, AGL2011-30170-C02-02] es_ES
dc.relation.ispartof Research in Veterinary Science es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Rabbit doe es_ES
dc.subject Immunological challenge es_ES
dc.subject Genetic selection es_ES
dc.subject Litter size es_ES
dc.subject Longevity es_ES
dc.subject.classification PRODUCCION ANIMAL es_ES
dc.subject.classification NUTRICION Y BROMATOLOGIA es_ES
dc.title Comparison of immune response to lipopolysaccharide of rabbit does selected for litter size at weaning or founded for reproductive longevity es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1016/j.rvsc.2013.01.008
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ciencia Animal - Departament de Ciència Animal es_ES
dc.contributor.affiliation Universitat Politècnica de València. Escuela Técnica Superior de Ingenieros Agrónomos - Escola Tècnica Superior d'Enginyers Agrònoms es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto de Ciencia y Tecnología Animal - Institut de Ciència i Tecnologia Animal es_ES
dc.description.bibliographicCitation Ferrian, S.; Blas Ferrer, E.; Larsen, T.; Sánchez Serrano, JP.; Friggens, NC.; Corpa, JM.; Baselga Izquierdo, M.... (2013). Comparison of immune response to lipopolysaccharide of rabbit does selected for litter size at weaning or founded for reproductive longevity. Research in Veterinary Science. 94(3):518-525. doi:10.1016/j.rvsc.2013.01.008 es_ES
dc.description.accrualMethod Senia es_ES
dc.relation.publisherversion http://dx.doi.org/10.1016/j.rvsc.2013.01.008 es_ES
dc.description.upvformatpinicio 518 es_ES
dc.description.upvformatpfin 525 es_ES
dc.type.version info:eu repo/semantics/publishedVersion es_ES
dc.description.volume 94 es_ES
dc.description.issue 3 es_ES
dc.relation.senia 239829 es_ES


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